Lari Federico, Giostra Fabrizio, Bragagni Gianpaolo, Di Battista Nicola
UO Medicina Interna, Ospedale SS Salvatore di San Giovanni in Persiceto: Azienda USL di Bologna.
Recenti Prog Med. 2011 Mar;102(3):114-9. doi: 10.1701/608.7067.
The application of a Continuous Positive pressure to Patient's airway (CPAP) represents one of the most important respiratory treatments during Acute Respiratory Failure (ARF) due to Acute Cardiogenic Pulmonary Edema (ACPE). Thanks to its hemodynamic and ventilatory effects, CPAP improves clinical and gasanalytic parameters and lead to a decrease of mortality and need of intubation in these patients. CPAP can be applied with different devices: ventilators, Venturi-like flow generators and Boussignac's device.
To verify and to compare effectiveness and tolerability of two different CPAP's devices (Venturi-like flow generator and Buossignac's device) in ARF due to ACPE. The study was performed in a General Medical Ward.
20 patients with ARF due to ACPE were randomized in two group: the first group (10 patients) received CPAP with a Venturi-like flow generator, the second group (10 patients) with Boussignac's device. At the end of CPAP treatment each patient gave a score to tolerability.
In each group we noted a significant (p<0.05) improvement in clinical and gasanalytic parameters since the first hour of treatment; these improvements were confirmed in following determinations and were not significantly different in the two group of patients. The Boussignac group showed a better tolerability.
The two CPAP's devices resulted similar in term of effectiveness. Boussignac's device has shown a better tolerability: this characteristic, together with the simple use, should stimulate the diffusion of this device where a flow generator or a ventilator are not present (outside Intensive Care Units, for example in General Medical Wards).
对因急性心源性肺水肿(ACPE)导致急性呼吸衰竭(ARF)的患者应用持续气道正压通气(CPAP)是最重要的呼吸治疗方法之一。由于其血流动力学和通气作用,CPAP可改善临床和气体分析参数,并降低这些患者的死亡率和插管需求。CPAP可通过不同设备应用:呼吸机、文丘里式气流发生器和布西尼亚克装置。
验证并比较两种不同CPAP设备(文丘里式气流发生器和布西尼亚克装置)对因ACPE导致的ARF的有效性和耐受性。该研究在普通内科病房进行。
20例因ACPE导致ARF的患者被随机分为两组:第一组(10例患者)使用文丘里式气流发生器接受CPAP治疗,第二组(10例患者)使用布西尼亚克装置。在CPAP治疗结束时,每位患者对耐受性进行评分。
在每组中,自治疗第一小时起,我们注意到临床和气体分析参数有显著(p<0.05)改善;这些改善在后续测定中得到证实,且两组患者之间无显著差异。布西尼亚克组显示出更好的耐受性。
两种CPAP设备在有效性方面结果相似。布西尼亚克装置显示出更好的耐受性:这一特性连同其使用简便,应会促进该装置在没有气流发生器或呼吸机的地方(例如在普通内科病房,而非重症监护病房)的推广。