Keske U, Cordes M, Wilfling M, Hunger J, Hosten N, Gahl G
Abteilung für Innere Medizin mit Schwerpunkt Nephrologie, Universitätsklinikum Rudolf Virchow, Standort Charlottenburg, Berlin, West.
Rofo. 1990 Mar;152(3):287-92. doi: 10.1055/s-2008-1046870.
Renal clearance of 99mTc-mercaptoacetyltriglycine (MAG3) and 131J-orthoidohippurate (OIH) were compared by simultaneous measurement in 50 patients. Renal time-activity-curves of both radiopharmaceuticals were compared in 50 patients. With regard to the clearance, good correlation (r = 0.95) with a mean ratio MAG3-/OIH-clearance of 0.62 was found. No significant difference between patients with normal (n = 30) and impaired (n = 20) renal function could be demonstrated. Renal time activity curves and relative renal function showed good correspondence in patients with normal (n = 13) and impaired (n = 7) renal function. It is concluded that MAG3 may be used as substitute for OIH in patients with normal and impaired renal function.
