Handa Victoria L, Whitcomb Emily, Weidner Alison C, Nygaard Ingrid, Brubaker Linda, Bradley Catherine S, Paraiso Marie Fidela R, Schaffer Joseph, Zyczynski Halina M, Zhang Min, Richter Holly E
Department of Gynecology and Obstetrics, Johns Hopkins School of Medicine, Baltimore, MD.
Female Pelvic Med Reconstr Surg. 2011;17(1):30-35. doi: 10.1097/SPV.0b013e318205e263.
(1) to describe sexual function in women seeking treatment of stress urinary incontinence (SUI); (2) to compare the impact on sexual function of three SUI treatments; and (3) to investigate whether non-surgical treatment of SUI is associated with improved sexual function. METHODS: Women with SUI were randomized to continence pessary, behavioral therapy (pelvic floor muscle training and continence strategies), or combination therapy. Sexual function was assessed at baseline and 3-months using short forms of the Pelvic Organ Prolapse-Urinary Incontinence Sexual Function Questionnaire (PISQ-12) and the Personal Experiences Questionnaire (SPEQ). Successful treatment of SUI was assessed with a patient global impression of improvement. ANOVA was used to compare scores between groups. RESULTS: At baseline, sexual function was worse among women with mixed incontinence compared to those with pure SUI. After therapy, successful treatment of SUI was associated with greater improvement in PISQ-12 score (2.26 ± 3.24 versus 0.48 ± 3.76, p=0.0007), greater improvement in incontinence with sexual activity (0.45 ± 0.84 versus 0.01 ± 0.71, p=0.0002), and greater reduction in restriction in sexual activity related to fear of incontinence (0.32 ± 0.76 versus -0.06 ± 0.78, p=0.0008). Among those successfully treated for SUI, improvement in continence during sexual activity was greater in both the combined therapy group (p=0.019) and the behavioral group (p=0.02) compared to the pessary group. CONCLUSIONS: Successful non-surgical treatment of SUI is associated with improvements in incontinence-specific measures of sexual function. Behavioral therapy may be preferred to pessary for treatment of SUI among women whose incontinence interferes with sexual function.
(1)描述寻求压力性尿失禁(SUI)治疗的女性的性功能;(2)比较三种SUI治疗方法对性功能的影响;(3)研究SUI的非手术治疗是否与性功能改善相关。方法:将患有SUI的女性随机分为使用阴道托、行为疗法(盆底肌肉训练和控尿策略)或联合疗法。在基线和3个月时,使用盆底器官脱垂-尿失禁性功能问卷(PISQ-12)简表和个人经历问卷(SPEQ)评估性功能。用患者总体改善印象评估SUI的成功治疗情况。采用方差分析比较组间得分。结果:在基线时,混合性尿失禁女性的性功能比单纯性SUI女性更差。治疗后,SUI的成功治疗与PISQ-12得分的更大改善相关(2.26±3.24对0.48±3.76,p = 0.0007),与性活动时尿失禁的更大改善相关(0.45±0.84对0.01±0.71,p = 0.0002),以及与因担心尿失禁而导致的性活动限制的更大减少相关(0.32±0.76对-0.06±0.78,p = 0.0008)。在成功治疗SUI的患者中,与阴道托组相比,联合治疗组(p = 0.019)和行为治疗组(p = 0.02)在性活动期间的控尿改善更大。结论:SUI的成功非手术治疗与性功能的尿失禁特异性指标改善相关。对于尿失禁干扰性功能的女性,行为疗法可能比阴道托更适合治疗SUI。