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因贫血导致的献血者延期:一项基于三级医疗中心的研究。

Donor deferral due to anemia: A tertiary care center-based study.

作者信息

Bahadur Shalini, Pujani Meenu, Jain Manjula

机构信息

Department of Pathology and Blood Bank, Lady Hardinge Medical College & Associated Hospitals, New Delhi, India.

出版信息

Asian J Transfus Sci. 2011 Jan;5(1):53-5. doi: 10.4103/0973-6247.76001.

DOI:10.4103/0973-6247.76001
PMID:21572718
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3082719/
Abstract

BACKGROUND

The minimum hemoglobin cutoff for blood donation in India is 12.5 gm% for both male and female donors and the minimum donation interval is 3 months. Donation of one unit of blood results in decrease in hemoglobin by 1 gm% and loss of 200-250 mg of iron. Donor deferral due to anemia is one of the major reasons of temporary rejection of blood donors. In the absence of further workup or advise, it results in loss of valuable donor base.

AIM AND OBJECTIVE

To provide baseline information regarding the prevalence and spectrum of anemia in prospective blood donors to help plan a future strategy for donor management.

MATERIALS AND METHODS

Hemoglobin testing of donors was performed using Hemocue and Copper sulfate specific gravity method. Ethylene diamine tetraacetic acid sample of all the donors who failed either or both the screening tests was tested on automated analyzer for evaluation of hemoglobin and red blood cell indices.

RESULTS

Of all the donors, 15.5% were deferred due to anemia. Prevalence of anemia in prospective blood donors was 1.8%. It was significantly higher in female donors compared with male donors (34.2% vs 1.2%). The most common type of anemia was normocytic normochromic.

摘要

背景

在印度,男性和女性献血者的最低血红蛋白临界值均为12.5克/百分比,最短献血间隔为3个月。捐献一个单位的血液会导致血红蛋白下降1克/百分比,并损失200 - 250毫克铁。因贫血导致的献血者延期是暂时拒绝献血者的主要原因之一。在没有进一步检查或建议的情况下,这会导致宝贵的献血者群体流失。

目的

提供有关未来献血者贫血患病率和类型的基线信息,以帮助制定未来献血者管理策略。

材料与方法

使用血红蛋白仪和硫酸铜比重法对献血者进行血红蛋白检测。对所有一项或两项筛查试验不合格的献血者的乙二胺四乙酸样本在自动分析仪上进行检测,以评估血红蛋白和红细胞指数。

结果

在所有献血者中,15.5%因贫血而延期。未来献血者中贫血的患病率为1.8%。女性献血者的贫血患病率显著高于男性献血者(34.2%对1.2%)。最常见的贫血类型是正细胞正色素性贫血。

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本文引用的文献

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2
Iron deficiency in frequent and first time female blood donors.频繁献血和初次献血女性中的缺铁情况。
East Afr J Public Health. 2008 Dec;5(3):157-9. doi: 10.4314/eajph.v5i3.38995.
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Anemia screening in potential female blood donors: comparison of two different quantitative methods.潜在女性献血者的贫血筛查:两种不同定量方法的比较。
Transfusion. 2009 Apr;49(4):662-8. doi: 10.1111/j.1537-2995.2008.02023.x. Epub 2009 Jan 2.
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Short-term ferrous sulfate supplementation in female blood donors.对女性献血者进行短期硫酸亚铁补充
Transfusion. 2008 Jun;48(6):1192-7. doi: 10.1111/j.1537-2995.2007.01671.x. Epub 2008 Mar 17.
5
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Transfus Med. 2007 Oct;17(5):379-83. doi: 10.1111/j.1365-3148.2007.00738.x. Epub 2007 Aug 23.
6
A study of serum ferritin levels among male blood donors in Hospital Universiti sains Malaysia.马来西亚理科大学医院男性献血者血清铁蛋白水平的研究。
Southeast Asian J Trop Med Public Health. 2006 Mar;37(2):370-3.
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The effect of repeated blood donations on the iron status of Iranian blood donors attending the Iranian blood transfusion organization.重复献血对参加伊朗输血组织的伊朗献血者铁状态的影响。
Int J Vitam Nutr Res. 2006 May;76(3):132-7. doi: 10.1024/0300-9831.76.3.132.
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