Gadewal Nikhil Sureshkumar, Zingde Surekha Mahesh
Bioinformation. 2011 May 7;6(4):169-70. doi: 10.6026/97320630006169.
The oral cancer gene database has been compiled to enable fast retrieval of updated information and role of the genes implicated in oral cancer. The first version of the database with 242 genes was published in Online Journal of Bioinformatics 8(1), 41-44, 2007. In the second version, the database has been enlarged to include 374 genes by adding 132 gene entries. The architecture and format of the database is similar to the earlier version, and includes updated information and external hyperlinks for all the genes. The functional gene interaction network for important biological processes and molecular functions has been rebuilt based on 374 genes using 'String 8.3'. The database is freely available at http://www.actrec.gov.in/OCDB/index.htm and provides the scientist information and external links for the genes involved in oral cancer, interactions between them, and their role in the biology of oral cancer along with clinical relevance.
口腔癌基因数据库的编纂目的是实现对与口腔癌相关基因的最新信息及作用的快速检索。该数据库的第一版包含242个基因,于2007年发表在《生物信息学在线期刊》第8卷第1期,第41 - 44页。在第二版中,通过添加132个基因条目,数据库已扩充至包含374个基因。数据库的架构和格式与早期版本相似,且包含所有基因的更新信息和外部超链接。基于374个基因,利用“String 8.3”重建了重要生物学过程和分子功能的功能基因相互作用网络。该数据库可在http://www.actrec.gov.in/OCDB/index.htm免费获取,为科学家提供了与口腔癌相关基因的信息和外部链接、这些基因之间的相互作用、它们在口腔癌生物学中的作用以及临床相关性。