Hunt S J, Santa Cruz D J, Miller C W
Cutaneous Pathology, St John's Mercy Medical Center, St Louis, MO 63141-8221.
Arch Dermatol. 1990 Apr;126(4):506-8.
A 63-year-old woman with fibrous histiocytomas showed cholesterol deposition in the setting of type IIB hyperlipidemia. The two lesions involved the left leg and right thigh. One had typical features of a fibrous histiocytoma including changes of the overlying epidermis. The other was essentially replaced by cholesterol deposits and could not be differentiated from a tuberous xanthoma. This case illustrates the histiocytic response of fibrous histiocytomas to a hyperlipoproteinemic microenvironment.
