Luis Quintanar J, Gutiérrez-García Karina, Castillo-Hernández Luis
Department of Physiology and Pharmacology, Laboratory of Neurophysiology, Centro de Ciencias Básicas, Universidad Autónoma de Aguascalientes, Av. Universidad 940, CP 20131 Aguascalientes, Mexico.
Invert Neurosci. 2011 Dec;11(2):113-6. doi: 10.1007/s10158-011-0120-7. Epub 2011 May 15.
We investigated whether the Gonadotropin-releasing hormone affects the spontaneous muscular contraction in the earthworm Eisenia foetida. In addition, we investigated the presence of Gonadotropin-releasing hormone receptor in ventral nerve cord by immunohistochemistry and polymerase chain reaction. Gonadotropin-releasing hormone induced a significant increase on both amplitude and muscular tone and decrease in the frequency of spontaneous muscular contraction. We found the presence of immunoreactive material to Gonadotropin-releasing hormone receptor in the ventral nerve cord, likewise the Gonadotropin-releasing hormone receptor mRNA expression. In conclusion, the Gonadotropin-releasing hormone modifies the spontaneous muscular contraction in E. foetida and these effects can be due to the activation of the Gonadotropin-releasing hormone receptor.
我们研究了促性腺激素释放激素是否会影响赤子爱胜蚓的自发肌肉收缩。此外，我们通过免疫组织化学和聚合酶链反应研究了腹神经索中促性腺激素释放激素受体的存在情况。促性腺激素释放激素导致自发肌肉收缩的幅度和肌张力显著增加，频率降低。我们发现腹神经索中存在促性腺激素释放激素受体的免疫反应性物质，同样也存在促性腺激素释放激素受体mRNA表达。总之，促性腺激素释放激素改变了赤子爱胜蚓的自发肌肉收缩，这些影响可能是由于促性腺激素释放激素受体的激活所致。
