• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

环境中的药品:教育视角。

Pharmaceuticals in the environment: an educational perspective.

机构信息

Gymnasium Ganderkesee, Am Steinacker 12, 27777 Ganderkesee, Germany.

出版信息

Environ Sci Pollut Res Int. 2011 Nov;18(9):1555-66. doi: 10.1007/s11356-011-0512-6. Epub 2011 May 15.

DOI:10.1007/s11356-011-0512-6
PMID:21573924
Abstract

PURPOSE

Pharmaceuticals are an integral part of a dignified life. However, a lack of degradability and threats to the welfare of living beings cause concern due to their emission into the environment. There is also a lack of knowledge about cause and consequence. Therefore, we intend to contribute to the development of educational programmes which should increasingly include the topic 'pharmaceuticals in the environment'.

METHODS

Considering the current literature, we developed a corresponding series of worksheets (Online Resource) and sample solutions on an introductory level and integrated them into our curriculum.

RESULTS

The material compiled for the worksheets was arranged in a logical order and considers several subtopics. The worksheets aim to support the examination of related aspects such as environmental effects, emissions, wastewater treatment plants, degradation, degradation by-products, advanced oxidation processes, hydraulic retention times, half-life times, biosolids, exposition pathways, precautionary principle, classification schemes for pharmaceuticals and, related to the structure-activity relationship, the design for degradability. The students managed to work on the tasks in an appropriate manner and received a good overview of the occurrence and fate of pharmaceuticals in the environment.

CONCLUSIONS

Tasks that were presented to students regarding the topic 'pharmaceuticals in the environment' contributed to a better understanding of the possible risks of medical care on an introductory level. The tasks have been incorporated into a logic series of worksheets (Online Resource) with sample solutions available. Alternatively, the material would be appropriate for the preparation of a corresponding lecture on this topic.

摘要

目的

药品是有尊严的生活的一个组成部分。然而,由于其排放到环境中,缺乏可降解性和对生物福利的威胁引起了人们的关注。人们对其原因和后果也缺乏了解。因此,我们希望为教育计划的发展做出贡献,这些计划应越来越多地包括“环境中的药品”这一主题。

方法

考虑到目前的文献,我们在入门水平上开发了相应的一系列工作表(在线资源)和示例解决方案,并将其纳入我们的课程。

结果

为工作表编制的材料是按逻辑顺序排列的,并考虑了几个子主题。工作表旨在支持对相关方面的检查,如环境影响、排放、废水处理厂、降解、降解副产物、高级氧化工艺、水力停留时间、半衰期、生物固体、暴露途径、预防原则、药品分类方案,以及与结构-活性关系相关的可降解性设计。学生能够以适当的方式完成任务,并对环境中药品的发生和命运有了很好的了解。

结论

向学生提出的关于“环境中的药品”这一主题的任务有助于在入门水平上更好地理解医疗保健的可能风险。这些任务已被纳入一个带有示例解决方案的逻辑系列工作表(在线资源)中。或者,该材料也适合于准备关于该主题的相应讲座。

相似文献

1
Pharmaceuticals in the environment: an educational perspective.环境中的药品:教育视角。
Environ Sci Pollut Res Int. 2011 Nov;18(9):1555-66. doi: 10.1007/s11356-011-0512-6. Epub 2011 May 15.
2
Experiences with the OECD 308 transformation test: a human pharmaceutical perspective.OECD 308 转化试验的经验:从人用药物角度看
Integr Environ Assess Manag. 2014 Jan;10(1):114-24. doi: 10.1002/ieam.1457. Epub 2013 Nov 21.
3
Pharmaceuticals in the environment in Italy: causes, occurrence, effects and control.意大利环境中的药物:成因、存在情况、影响及控制
Environ Sci Pollut Res Int. 2006 Jan;13(1):15-21. doi: 10.1065/espr2006.01.004.
4
Removal of pharmaceuticals during wastewater treatment and environmental risk assessment using hazard indexes.污水处理过程中药物的去除及利用危害指数进行的环境风险评估。
Environ Int. 2010 Jan;36(1):15-26. doi: 10.1016/j.envint.2009.09.002. Epub 2009 Oct 12.
5
Fate and removal of pharmaceuticals and illicit drugs in conventional and membrane bioreactor wastewater treatment plants and by riverbank filtration.传统和膜生物反应器污水处理厂及河岸过滤中药物和非法药物的归宿与去除
Philos Trans A Math Phys Eng Sci. 2009 Oct 13;367(1904):3979-4003. doi: 10.1098/rsta.2009.0105.
6
Practical overview of analytical methods for endocrine-disrupting compounds, pharmaceuticals and personal care products in water and wastewater.水和废水中内分泌干扰化合物、药物及个人护理产品分析方法的实用概述。
Philos Trans A Math Phys Eng Sci. 2009 Oct 13;367(1904):3923-39. doi: 10.1098/rsta.2009.0111.
7
Sources, pathways, and relative risks of contaminants in surface water and groundwater: a perspective prepared for the Walkerton inquiry.地表水和地下水中污染物的来源、途径及相对风险:为沃克顿调查准备的一份报告
J Toxicol Environ Health A. 2002 Jan 11;65(1):1-142. doi: 10.1080/152873902753338572.
8
Occurrence patterns of pharmaceuticals in water and wastewater environments.药品在水和废水环境中的出现模式。
Anal Bioanal Chem. 2007 Feb;387(4):1225-34. doi: 10.1007/s00216-006-1035-8. Epub 2007 Jan 5.
9
Estimation of the cancer risk to humans resulting from the presence of cyclophosphamide and ifosfamide in surface water.估算地表水存在的环磷酰胺和异环磷酰胺对人类的癌症风险。
Environ Sci Pollut Res Int. 2010 Feb;17(2):486-96. doi: 10.1007/s11356-009-0195-4. Epub 2009 Jun 24.
10
Are pharmaceuticals potent environmental pollutants? Part I: environmental risk assessments of selected active pharmaceutical ingredients.药品是强效环境污染物吗?第一部分:选定活性药物成分的环境风险评估。
Sci Total Environ. 2006 Jul 1;364(1-3):67-87. doi: 10.1016/j.scitotenv.2005.06.035. Epub 2005 Oct 27.

引用本文的文献

1
Green pharmacy - a narrative review.绿色药房——一篇叙述性综述。
Clujul Med. 2018 Oct;91(4):391-398. doi: 10.15386/cjmed-1129. Epub 2018 Oct 30.
2
Consumer-perceived risks and choices about pharmaceuticals in the environment: a cross-sectional study.消费者对环境中药品的感知风险和选择:一项横断面研究。
Environ Health. 2013 Jun 5;12:45. doi: 10.1186/1476-069X-12-45.

本文引用的文献

1
Toward a comprehensive molecular design framework for reduced hazard.迈向降低危害的综合分子设计框架。
Chem Rev. 2010 Oct 13;110(10):5845-82. doi: 10.1021/cr9003105.
2
Antiviral drugs in wastewater and surface waters: a new pharmaceutical class of environmental relevance?废水中和地表水中的抗病毒药物:一种新的具有环境相关性的药物类别?
Environ Sci Technol. 2010 Mar 1;44(5):1728-35. doi: 10.1021/es903216p.
3
Highly active human pharmaceuticals in aquatic systems: A concept for their identification based on their mode of action.
水中高活性人体药物:基于作用模式识别此类物质的概念。
Aquat Toxicol. 2010 Feb 18;96(3):167-81. doi: 10.1016/j.aquatox.2009.11.021. Epub 2009 Dec 21.
4
Ecotoxicological aspects related to the presence of pharmaceuticals in the aquatic environment.与水生环境中药物存在相关的生态毒理学方面。
J Hazard Mater. 2010 Mar 15;175(1-3):45-95. doi: 10.1016/j.jhazmat.2009.10.100. Epub 2009 Oct 30.
5
Environmental risk assessment of pharmaceuticals in rivers: relationships between hazard indexes and aquatic macroinvertebrate diversity indexes in the Llobregat River (NE Spain).河流中药物的环境风险评估:在西班牙东北部 Llobregat 河流中,危害指数与水生大型无脊椎动物多样性指数之间的关系。
Environ Int. 2010 Feb;36(2):153-62. doi: 10.1016/j.envint.2009.10.003. Epub 2009 Nov 20.
6
Occurrence and fate of human pharmaceuticals in the environment.环境中人类药物的存在与归宿
Rev Environ Contam Toxicol. 2010;202:53-154. doi: 10.1007/978-1-4419-1157-5_2.
7
Alternative solvent-free methodologies in the synthesis of pharmaceutical drugs.药物合成中的替代无溶剂方法。
Curr Opin Drug Discov Devel. 2009 Nov;12(6):772-83.
8
Removal of pharmaceuticals during wastewater treatment and environmental risk assessment using hazard indexes.污水处理过程中药物的去除及利用危害指数进行的环境风险评估。
Environ Int. 2010 Jan;36(1):15-26. doi: 10.1016/j.envint.2009.09.002. Epub 2009 Oct 12.
9
Organic contaminants in sewage sludge (biosolids) and their significance for agricultural recycling.污水污泥(生物固体)中的有机污染物及其在农业循环利用中的意义。
Philos Trans A Math Phys Eng Sci. 2009 Oct 13;367(1904):4005-41. doi: 10.1098/rsta.2009.0154.
10
Fate and removal of pharmaceuticals and illicit drugs in conventional and membrane bioreactor wastewater treatment plants and by riverbank filtration.传统和膜生物反应器污水处理厂及河岸过滤中药物和非法药物的归宿与去除
Philos Trans A Math Phys Eng Sci. 2009 Oct 13;367(1904):3979-4003. doi: 10.1098/rsta.2009.0105.