Urology Clinic, University Clinical Center Nis, Hajduk Stanka 8/49, 18 000 Nis, Serbia.
Hernia. 2011 Dec;15(6):685-90. doi: 10.1007/s10029-011-0829-6. Epub 2011 May 15.
Although grafts can be made from the same materials, the final weave of the product may play a role in the ultimate outcomes or complications. The aim of this experimental study is to evaluate and compare the mechanical properties of the meshes and their influence on biological characteristics as well.
Full-thickness abdominal wall defect with respect to the peritoneum was primary repaired in 144 male Wister rats using the overlay technique. Monofilament, multifilament and coated polypropylene grafts were used for the repairs. Graft shrinkage, thickness and tensile strength of the explants were analysed after 3 and 6 weeks.
Monofilament grafts showed the highest shrinkage level of 11.97-18% during the investigated period. The thickness of monofilament explants increased gradually, with a maximum of 25.35% after 6 weeks. Multifilament and collagen explants did swell more rapidly in the third week, decreasing thereafter to 19.63-23.04% above the pre-implantation values after 6 weeks. The tensile strength showed a gradual increase over the course of the experiment in all groups.
After graft stabilisation, all samples had similar strength, regardless of the significant differences in the pre-implantation values of graft strength.
尽管移植物可以使用相同的材料制成，但最终产品的编织方式可能会对最终结果或并发症产生影响。本实验研究旨在评估和比较网片的机械性能及其对生物学特性的影响。
使用覆盖技术对 144 只雄性 Wistar 大鼠的全层腹壁缺损进行腹膜修复。使用单丝、多丝和涂覆的聚丙烯移植物进行修复。在 3 周和 6 周后分析移植物的收缩、厚度和拉伸强度。
在研究期间，单丝移植物的收缩率最高，为 11.97-18%。单丝标本的厚度逐渐增加，6 周后达到最大值 25.35%。多丝和胶原标本在前 3 周更快地膨胀，然后在 6 周后减少到植入前值的 19.63-23.04%以上。所有组的拉伸强度在实验过程中逐渐增加。
在移植物稳定后，所有样本的强度相似，尽管移植物强度的植入前值存在显著差异。
