Department of Internal Medicine, Section of Nephrology, Haydarpaşa Numune Training and Research Hospital, Istanbul, Turkey.
Ren Fail. 2011;33(5):531-3. doi: 10.3109/0886022X.2011.577543.
A 30-year-old woman was diagnosed with ulcerative colitis in January 2006. One year later, she presented because of severe back pain and was diagnosed with ankylosing spondylitis (AS). In February 2008, the patient, while still under standard treatment for ulcerative colitis and AS, was admitted because of massive proteinuria and related symptoms. Nephrotic syndrome was observed and renal biopsy revealed amyloid deposits. After treatment with infliximab, nephrotic syndrome disappeared. We aim to present a case of secondary amyloidosis complicating ulcerative colitis and associated spondyloarthropathy.
一位 30 岁女性于 2006 年 1 月被诊断为溃疡性结肠炎。一年后，她因严重背痛就诊，并被诊断为强直性脊柱炎（AS）。2008 年 2 月，该患者在溃疡性结肠炎和 AS 的标准治疗下，因大量蛋白尿和相关症状住院。观察到肾病综合征，肾活检显示淀粉样物质沉积。使用英夫利昔单抗治疗后，肾病综合征消失。我们旨在报告一例溃疡性结肠炎并发脊柱关节病的继发性淀粉样变性病例。
