Castellano I, Gómez-Martino J R, Hernández M T, Novillo R, Covarsí A
Sección de Nefrología, Hospital San Pedro de Alcántara, Cáceres.
Nefrologia. 2001 Jan-Feb;21(1):88-91.
Secondary systemic amyloidosis is a frequent complication in several chronic infectious and inflammatory states. Although initially amyloidosis was described in association with long-standing syphilis and tuberculosis, with the introduction of antiboitic and antituberculous therapy, rheumatoid arthritis is now the commonest cause of this illness. We present here the case of a 16 year-old woman, who was diagnosed one month ealier with pulmonary tuberculosis. She developed a nephrotic syndrome and her kidney biopsy confirmed the presence of amyloid. Treatment of the tuberculosis was accompanied by clinical remission of the nephrotic syndrome two years later.
继发性系统性淀粉样变性是几种慢性感染和炎症状态下常见的并发症。虽然最初淀粉样变性是与长期梅毒和结核病相关联被描述的,但随着抗生素和抗结核治疗的引入,类风湿性关节炎现在是这种疾病最常见的病因。我们在此呈现一名16岁女性的病例,她一个月前被诊断为肺结核。她出现了肾病综合征,肾脏活检证实存在淀粉样物质。对结核病的治疗伴随着两年后肾病综合征的临床缓解。