患者的直接体验是安慰剂镇痛的核心要素。
Patients' direct experiences as central elements of placebo analgesia.
机构信息
Department of Psychology, Aarhus University, Jens Christian Skous Vej 4, 8000 Aarhus C, Denmark.
出版信息
Philos Trans R Soc Lond B Biol Sci. 2011 Jun 27;366(1572):1913-21. doi: 10.1098/rstb.2010.0402.
Abstract
Placebo analgesic effects appear to be related to patients' perception of the therapeutic intervention. In this paper, we review quantitative findings of how the relationship with the physician and the verbal suggestions given for relief may influence patients' perception of a treatment and how patients' expectations and emotional feelings may affect treatment outcome. We also present qualitative data from interviews with patients who have experienced pain relief following a placebo or an active treatment. A special focus is given to the temporal development of placebo analgesia at psychological and neurophysiological levels. Finally, we discuss the extent to which the quantitative and qualitative findings supplement or contrast with each other, and we touch upon possible implications of patients' direct experience as central for placebo analgesia.
摘要
安慰剂的镇痛效果似乎与患者对治疗干预的感知有关。本文综述了与医生的关系以及为缓解疼痛而给出的口头建议如何影响患者对治疗的感知，以及患者的期望和情绪感受如何影响治疗效果的定量研究结果。我们还介绍了对经历过安慰剂或积极治疗后疼痛缓解的患者进行访谈的定性数据。特别关注心理和神经生理学水平上安慰剂镇痛的时间发展。最后，我们讨论了定量和定性研究结果在多大程度上相互补充或对比，并探讨了患者的直接体验作为安慰剂镇痛的核心的可能意义。
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