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3-乙酰基-6-氯-4-苯基喹啉-2(1H)-酮

3-Acetyl-6-chloro-4-phenyl-quinolin-2(1H)-one.

作者信息

Sundar J Kalyana, Natarajan S, Sarveswari S, Vijayakumar V, Lakshman P L Nilantha

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2009 Dec 24;66(Pt 1):o228. doi: 10.1107/S1600536809054087.

DOI:10.1107/S1600536809054087
PMID:21580109
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2980191/
Abstract

The title compound, C(17)H(12)ClNO(2), crystallizes with two mol-ecules in the asymmetric unit. The main conformational difference between these two mol-ecules is the dihedral angle between the phenyl ring and the quinoline ring system [70.5 (1)° and 65.5 (1) Å]. The crystal packing is stabilized by N-H⋯O hydrogen bonds.

摘要

标题化合物C(17)H(12)ClNO(2)在不对称单元中含有两个分子。这两个分子之间的主要构象差异在于苯环与喹啉环系统之间的二面角[70.5 (1)°和65.5 (1) Å]。晶体堆积通过N-H⋯O氢键得以稳定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ccb/2980191/e13db563655d/e-66-0o228-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ccb/2980191/e13db563655d/e-66-0o228-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ccb/2980191/e13db563655d/e-66-0o228-fig1.jpg

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1,4-Dihydropyridines as antagonists of platelet activating factor. 1. Synthesis and structure-activity relationships of 2-(4-heterocyclyl)phenyl derivatives.1,4 - 二氢吡啶类化合物作为血小板活化因子拮抗剂。1. 2-(4-杂环基)苯基衍生物的合成及构效关系
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