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1-{6-氯-2-[(2-氯-6-甲基喹啉-3-基)甲氧基]-4-苯基喹啉-3-基}乙酮

1-{6-Chloro-2-[(2-chloro-6-methyl-quinolin-3-yl)meth-oxy]-4-phenyl-quinolin-3-yl}ethanone.

作者信息

Khan F Nawaz, Hathwar Venkatesha R, Kumar Rajesh, Kushwaha Atul Kumar, Akkurt Mehmet

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 18;66(Pt 7):o1693-4. doi: 10.1107/S1600536810022701.

DOI:10.1107/S1600536810022701
PMID:21587915
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3006731/
Abstract

In the title compound, C(28)H(20)Cl(2)N(2)O(2), the 2-chloro-quinoline and 6-chloro-quinoline ring systems are twisted slightly, making a dihedral angle of 4.05 (3)°. The dihedral angle between the 2-quinoline ring system and the phenyl ring attached to it is 74.43 (5)°. In the crystal structure, a pair of inter-molecular C-H⋯O hydrogen bonds connect the mol-ecules, forming centrosymmetric dimers with R(2) (2)(16) motifs. The dimers are further consolidated by a C-H⋯π inter-action and a π-π stacking inter-action with a centroid-centroid distance of 3.6562 (10) Å.

摘要

在标题化合物C(28)H(20)Cl(2)N(2)O(2)中，2-氯喹啉和6-氯喹啉环系统略有扭曲，二面角为4.05 (3)°。2-喹啉环系统与其相连的苯环之间的二面角为74.43 (5)°。在晶体结构中，一对分子间C-H⋯O氢键连接分子，形成具有R(2) (2)(16) motif的中心对称二聚体。这些二聚体通过C-H⋯π相互作用和质心距离为3.6562 (10) Å的π-π堆积相互作用进一步巩固。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e6a/3006731/7d70a0bf7192/e-66-o1693-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e6a/3006731/b17824a58a37/e-66-o1693-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e6a/3006731/7d70a0bf7192/e-66-o1693-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e6a/3006731/b17824a58a37/e-66-o1693-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e6a/3006731/7d70a0bf7192/e-66-o1693-fig2.jpg

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