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本文引用的文献

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A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
2
N-[(R)-1-(2-hydroxy-5-methylphenyl)ethyl]-N-[(R)-1-(2-methoxy-5-methylphenyl)-2-phenylethyl]aminium chloride.N-[(R)-1-(2-羟基-5-甲基苯基)乙基]-N-[(R)-1-(2-甲氧基-5-甲基苯基)-2-苯乙基]氯化铵
Acta Crystallogr C. 2005 Apr;61(Pt 4):o262-4. doi: 10.1107/S0108270105005676. Epub 2005 Mar 25.
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A new 1,1'-binaphthyl-based catalyst for the enantioselective phenylacetylene addition to aromatic aldehydes without using a titanium complex.
Org Lett. 2002 Dec 12;4(25):4555-7. doi: 10.1021/ol027110q.
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1,2-Amino Alcohols and Their Heterocyclic Derivatives as Chiral Auxiliaries in Asymmetric Synthesis.1,2-氨基醇及其杂环衍生物作为不对称合成中的手性助剂
Chem Rev. 1996 Mar 28;96(2):835-876. doi: 10.1021/cr9500038.
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Solvent-free asymmetric aminoalkylation of electron-rich aromatic compounds: stereoselective synthesis of aminoalkylnaphthols by crystallization-induced asymmetric transformation.富电子芳香化合物的无溶剂不对称氨基烷基化反应：通过结晶诱导不对称转化立体选择性合成氨基烷基萘酚
J Org Chem. 2001 Jul 13;66(14):4759-65. doi: 10.1021/jo0101205.

4-氯-2-((1R)-1-{[(R)-(2-氯苯基)(环戊基)甲基]氨基}乙基)苯酚

4-Chloro-2-((1R)-1-{[(R)-(2-chloro-phen-yl)(cyclo-pent-yl)meth-yl]amino}eth-yl)phenol.

作者信息

Zhang Guang-You, Yang Ting, Xu Bao-Wang, Chen Di-Juan, Wang Wan-Hui

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2008 Oct 25;64(Pt 11):o2211-2. doi: 10.1107/S1600536808034624.

DOI:10.1107/S1600536808034624
PMID:21581069
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2959664/
Abstract

The title compound, C(20)H(23)Cl(2)NO, was prepared by condensation of (R)-1-(2-chloro-phen-yl)-1-cyclo-pentyl-methanamine with 1-(5-chloro-2-hydroxy-phen-yl)ethanone, resulting in the formation of a new chiral center. The structural analysis confirms the absolute configuration of the title compound and the formation of the (R,R) diastereoisomer. There is an intra-molecular O-H⋯N hydrogen bond which stabilizes the conformation of the mol-ecule. The mol-ecules are linked to each other through weak C-H⋯π inter-actions.

摘要

标题化合物C(20)H(23)Cl(2)NO是通过(R)-1-(2-氯苯基)-1-环戊基甲胺与1-(5-氯-2-羟基苯基)乙酮缩合制备的，从而形成了一个新的手性中心。结构分析确定了标题化合物的绝对构型以及(R,R)非对映异构体的形成。分子内存在O-H⋯N氢键，该氢键稳定了分子的构象。分子通过弱C-H⋯π相互作用相互连接。