• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

3-苯基-2-(哌啶-1-基)-3,5,6,8-四氢-4H-硫代吡喃并[3',4':2,3]噻吩并[5,4-d]嘧啶-4-酮

3-Phenyl-2-(piperidin-1-yl)-3,5,6,8-tetra-hydro-4H-thio-pyrano[3',4':2,3]thieno[5,4-d]pyrimidin-4-one.

作者信息

Xie Hai, Meng Shuang-Ming, Fan Yue-Qin, Guo Yong

机构信息

College of Chemistry and Chemical Engineering, ShanXi Datong University, Datong, Shanxi 037009, People's Republic of China.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2008 Nov 26;64(Pt 12):o2434. doi: 10.1107/S1600536808038683.

DOI:10.1107/S1600536808038683
PMID:21581402
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2959906/
Abstract

In the title compound, C(20)H(21)N(3)OS(2), the piperidinyl ring has a distorted chair conformation. Weak inter-molecular C-H⋯O hydrogen bonds link the mol-ecules into centrosymmetric dimers. The crystal packing exhibits short inter-molecular S⋯S distances of 3.590 (2) Å.

摘要

在标题化合物C₂₀H₂₁N₃OS₂中，哌啶基环具有扭曲的椅式构象。弱的分子间C—H⋯O氢键将分子连接成中心对称的二聚体。晶体堆积显示出分子间S⋯S的短距离为3.590(2) Å。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67c7/2959906/f917313ac46b/e-64-o2434-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67c7/2959906/b4ded0704b3b/e-64-o2434-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67c7/2959906/f917313ac46b/e-64-o2434-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67c7/2959906/b4ded0704b3b/e-64-o2434-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67c7/2959906/f917313ac46b/e-64-o2434-fig2.jpg

相似文献

1
3-Phenyl-2-(piperidin-1-yl)-3,5,6,8-tetra-hydro-4H-thio-pyrano[3',4':2,3]thieno[5,4-d]pyrimidin-4-one.3-苯基-2-(哌啶-1-基)-3,5,6,8-四氢-4H-硫代吡喃并[3',4':2,3]噻吩并[5,4-d]嘧啶-4-酮
Acta Crystallogr Sect E Struct Rep Online. 2008 Nov 26;64(Pt 12):o2434. doi: 10.1107/S1600536808038683.
2
{1-[(2-Oxidonaphthalen-1-yl)methylidene]thiosemicarbazidato-κN,O,S}diphenyl-tin(IV).{1-[(2-氧化萘-1-亚基)亚甲基]硫代氨基脲合-κN,O,S}二苯基锡(IV)
Acta Crystallogr Sect E Struct Rep Online. 2011 Jan 8;67(Pt 2):m145. doi: 10.1107/S1600536810054024.
3
3-Phenyl-2-(pyrrolidin-1-yl)-5,6-dihydro-8H-thio-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one.3-苯基-2-(吡咯烷-1-基)-5,6-二氢-8H-硫代吡喃并[4',3':4,5]噻吩并[2,3-d]嘧啶-4(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2010 Aug 25;66(Pt 9):o2403. doi: 10.1107/S1600536810032794.
4
2-Dicyclo-hexyl-amino-3-phenyl-5,6-di-hydro-8H-thio-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one.2-二环己基氨基-3-苯基-5,6-二氢-8H-硫代吡喃并[4',3':4,5]噻吩并[2,3-d]嘧啶-4(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Apr 1;67(Pt 4):o888. doi: 10.1107/S1600536811009226. Epub 2011 Mar 15.
5
Crystal structures of two hydrazinecarbo-thio-amide derivatives: (E)-N-ethyl-2-[(4-oxo-4H-chromen-3-yl)methyl-idene]hydrazinecarbo-thio-amide hemi-hydrate and (E)-2-[(4-chloro-2H-chromen-3-yl)methyl-idene]-N-phenyl-hydrazinecarbo-thio-amide.两种肼基碳硫酰胺衍生物的晶体结构：（E）-N-乙基-2-[(4-氧代-4H-色烯-3-基)亚甲基]肼基碳硫酰胺半水合物和（E）-2-[(4-氯-2H-色烯-3-基)亚甲基]-N-苯基肼基碳硫酰胺
Acta Crystallogr E Crystallogr Commun. 2015 Feb 21;71(Pt 3):305-8. doi: 10.1107/S2056989015003369. eCollection 2015 Mar 1.
6
Ethyl 4-(2,4-difluoro-phen-yl)-6-methyl-1-phenyl-2-thioxo-1,2,3,4-tetra-hydro-pyrimidine-5-carboxyl-ate.4-(2,4-二氟苯基)-6-甲基-1-苯基-2-硫代-1,2,3,4-四氢嘧啶-5-羧酸乙酯
Acta Crystallogr Sect E Struct Rep Online. 2009 Apr 8;65(Pt 5):o981-2. doi: 10.1107/S160053680901232X.
7
5-(4-Chloro-phen-yl)-1-methyl-3-phenyl-3,6,8,9-tetra-hydro-pyrazolo-[3,4-b]thio-pyrano[4,3-d]pyridine.5-（4-氯苯基）-1-甲基-3-苯基-3,6,8,9-四氢-吡唑并[3,4-b]硫代吡喃并[4,3-d]吡啶
Acta Crystallogr Sect E Struct Rep Online. 2011 Sep 1;67(Pt 9):o2421-2. doi: 10.1107/S1600536811033514. Epub 2011 Aug 27.
8
2-(2-Nitro-anilino)-5,6,7,8-tetra-hydro-4H-cyclo-hepta-[b]thio-phene-3-carbonitrile.2-（2-硝基苯胺基）-5,6,7,8-四氢-4H-环庚并[b]噻吩-3-腈
Acta Crystallogr Sect E Struct Rep Online. 2010 May 15;66(Pt 6):o1350-1. doi: 10.1107/S1600536810017149.
9
2-(Dibutyl-amino)-3-(4-fluoro-phen-yl)-5,6,7,8-tetra-hydro-7-methyl-6,8-di-phenyl-pyridine-[3',4':2,3]thieno[5,4-d]pyrimidin-4(3H)-one.2-（二丁基氨基）-3-（4-氟苯基）-5,6,7,8-四氢-7-甲基-6,8-二苯基吡啶-[3',4':2,3]噻吩并[5,4-d]嘧啶-4（3H）-酮
Acta Crystallogr Sect E Struct Rep Online. 2008 Jan 30;64(Pt 2):o535. doi: 10.1107/S1600536808002845.
10
rac-6-Hy-droxy-4-(4-nitro-phen-yl)-5-(2-thienyl-carbon-yl)-6-(trifluoro-meth-yl)-3,4,5,6-tetra-hydro-pyrimidin-2(1H)-one monohydrate.
Acta Crystallogr Sect E Struct Rep Online. 2010 Oct 23;66(Pt 11):o2932-3. doi: 10.1107/S1600536810041589.

引用本文的文献

1
7-Benzyl-3-(4-fluoro-phen-yl)-2-propyl-amino-5,6,7,8-tetra-hydro-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one.7-苄基-3-(4-氟苯基)-2-丙基氨基-5,6,7,8-四氢吡啶并[4',3':4,5]噻吩并[2,3-d]嘧啶-4(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2012 Apr 1;68(Pt 4):o1097. doi: 10.1107/S1600536812010318. Epub 2012 Mar 17.
2
7-Benzyl-3-(4-chloro-phen-yl)-2-isobutyl-amino-5,6,7,8-tetra-hydro-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one.7-苄基-3-(4-氯苯基)-2-异丁基氨基-5,6,7,8-四氢吡啶并[4',3':4,5]噻吩并[2,3-d]嘧啶-4(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2012 Mar 1;68(Pt 3):o822. doi: 10.1107/S1600536812007246. Epub 2012 Feb 24.
3

本文引用的文献

1
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
2
Synthesis and preliminary evaluation of some N-[5-(2-furanyl)-2-methyl-4-oxo-4H-thieno[2,3-d]pyrimidin-3-yl]-carboxamide and 3-substituted-5-(2-furanyl)-2-methyl-3H-thieno[2,3-d]pyrimidin-4-ones as antimicrobial agents.某些N-[5-(2-呋喃基)-2-甲基-4-氧代-4H-噻吩并[2,3-d]嘧啶-3-基] -羧酰胺和3-取代-5-(2-呋喃基)-2-甲基-3H-噻吩并[2,3-d]嘧啶-4-酮作为抗菌剂的合成与初步评价
Eur J Med Chem. 2003 Jan;38(1):89-100. doi: 10.1016/s0223-5234(02)01442-3.
7-Benzyl-2-[(cyclo-propyl-meth-yl)amino]-3-phenyl-5,6,7,8-tetra-hydro-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one.
7-苄基-2-[(环丙基甲基)氨基]-3-苯基-5,6,7,8-四氢吡啶并[4',3':4,5]噻吩并[2,3-d]嘧啶-4(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Aug 1;67(Pt 8):o2191. doi: 10.1107/S1600536811029771. Epub 2011 Jul 30.
4
7-Benzyl-3-(4-fluoro-phen-yl)-2-(pyrrol-idin-1-yl)-5,6,7,8-tetra-hydro-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one.7-苄基-3-(4-氟苯基)-2-(吡咯烷-1-基)-5,6,7,8-四氢吡啶并[4',3':4,5]噻吩并[2,3-d]嘧啶-4(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Sep 1;67(Pt 9):o2228. doi: 10.1107/S1600536811030625. Epub 2011 Aug 2.
5
2-Dicyclo-hexyl-amino-3-phenyl-5,6-di-hydro-8H-thio-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one.2-二环己基氨基-3-苯基-5,6-二氢-8H-硫代吡喃并[4',3':4,5]噻吩并[2,3-d]嘧啶-4(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Apr 1;67(Pt 4):o888. doi: 10.1107/S1600536811009226. Epub 2011 Mar 15.
6
3-Phenyl-2-(pyrrolidin-1-yl)-5,6-dihydro-8H-thio-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one.3-苯基-2-(吡咯烷-1-基)-5,6-二氢-8H-硫代吡喃并[4',3':4,5]噻吩并[2,3-d]嘧啶-4(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2010 Aug 25;66(Pt 9):o2403. doi: 10.1107/S1600536810032794.
7
3-Isopropyl-2-p-tol-yloxy-5,6,7,8-tetra-hydro-1-benzothieno[2,3-d]pyrimidin-4(3H)-one.3-异丙基-2-对甲苯氧基-5,6,7,8-四氢-1-苯并噻吩并[2,3-d]嘧啶-4(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2009 Apr 30;65(Pt 5):o1142-3. doi: 10.1107/S1600536809014962.
8
Ethyl 2-(3,3-dibutyl-thio-ureido)-4,5,6,7-tetra-hydro-benzo[b]thio-phene-3-carboxyl-ate.2-(3,3-二丁基硫代脲基)-4,5,6,7-四氢苯并[b]噻吩-3-羧酸乙酯
Acta Crystallogr Sect E Struct Rep Online. 2009 Nov 14;65(Pt 12):o3094-5. doi: 10.1107/S1600536809047230.