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7-苄基-2-[(环丙基甲基)氨基]-3-苯基-5,6,7,8-四氢吡啶并[4',3':4,5]噻吩并[2,3-d]嘧啶-4(3H)-酮

7-Benzyl-2-[(cyclo-propyl-meth-yl)amino]-3-phenyl-5,6,7,8-tetra-hydro-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one.

作者信息

Chen Hong

机构信息

College of Chemistry and Life Science, China Three Gorges University, Yichang 443002, People's Republic of China.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2011 Aug 1;67(Pt 8):o2191. doi: 10.1107/S1600536811029771. Epub 2011 Jul 30.

DOI:10.1107/S1600536811029771
PMID:22091199
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3213622/
Abstract

There are two independent mol-ecules in the asymmetric unit of the title compound, C(26)H(26)N(4)OS. In each mol-ecule, the thienopyrimidine fused-ring system is essentially planar with a maximum deviation of 0.0409 (18) for the N atom. In one mol-ecule, this ring system forms diherdral angles of 84.8 (1) and 67.6 (1)° with the adjacent phenyl and benzyl rings, respectively, while the corresponding angles in the other mol-ecule are 77.9 (1) and 66.5 (1)°.

摘要

标题化合物C(26)H(26)N(4)OS的不对称单元中有两个独立的分子。在每个分子中，噻吩并嘧啶稠环系统基本呈平面状，N原子的最大偏差为0.0409 (18) Å。在一个分子中，该环系统与相邻的苯环和苄基环分别形成84.8 (1)°和67.6 (1)°的二面角，而另一个分子中的相应角度分别为77.9 (1)°和66.5 (1)°。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78be/3213622/3eb253e776dd/e-67-o2191-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78be/3213622/94dd01f73b8b/e-67-o2191-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78be/3213622/3eb253e776dd/e-67-o2191-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78be/3213622/94dd01f73b8b/e-67-o2191-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78be/3213622/3eb253e776dd/e-67-o2191-fig2.jpg

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本文引用的文献

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