冈田酸：一种用于细胞调节研究的新型探针。
Okadaic acid: a new probe for the study of cellular regulation.
作者信息
Cohen P, Holmes C F, Tsukitani Y
机构信息
Department of Biochemistry, University of Dundee, UK.
出版信息
Trends Biochem Sci. 1990 Mar;15(3):98-102. doi: 10.1016/0968-0004(90)90192-e.
PMID:2158158
Abstract
The tumour promoter okadaic acid is a potent and specific inhibitor of protein phosphatases 1 and 2A. Here we review recent studies which demonstrate that this toxin is extremely useful for identifying biological processes that are controlled through the reversible phosphorylation of proteins.
摘要
肿瘤促进剂冈田酸是蛋白磷酸酶1和2A的一种强效且特异性抑制剂。在此，我们综述了近期的研究，这些研究表明这种毒素对于识别通过蛋白质可逆磷酸化所控制的生物学过程极为有用。
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