Shuai Jun, Liu Ying, Liu Mo, Liu Dengke
Acta Crystallogr Sect E Struct Rep Online. 2009 Jan 10;65(Pt 2):o269. doi: 10.1107/S1600536809000427.
The title compound, crystallized as a methanol solvate, C(18)H(20)O(2)·CH(3)OH, is an inter-mediate in the synthesis of the anti-lipidemic agent clinofibrate. Mol-ecules are packed together with the methanol solvent molecule via two O-H⋯O hydrogen bonds. The third O-H⋯O hydrogen bond is between neighboring 4,4'-(cyclo-hexane-1,1-di-yl)diphenol mol-ecules. The dihedral angle between two benzene rings planes is 81.69 (6).
标题化合物以甲醇溶剂化物C(18)H(20)O(2)·CH(3)OH的形式结晶，是抗血脂药物氯贝丁酯合成中的中间体。分子通过两个O-H⋯O氢键与甲醇溶剂分子堆积在一起。第三个O-H⋯O氢键存在于相邻的4,4'-(环己烷-1,1-二亚基)二苯酚分子之间。两个苯环平面之间的二面角为81.69 (6)。
