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4-（4-甲氧基苯基）-3-[2-（2-甲氧基苯基）乙基]-1H-1,2,4-三唑-5（4H）-酮

4-(4-Methoxy-phen-yl)-3-[2-(2-methoxy-phen-yl)eth-yl]-1H-1,2,4-triazol-5(4H)-one.

作者信息

Hanif Muhammad, Qadeer Ghulam, Rama Nasim Hasan, Akhtar Javeed, Helliwell Madeleine

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2009 Jan 31;65(Pt 2):o429. doi: 10.1107/S1600536809002815.

DOI:10.1107/S1600536809002815
PMID:21582015
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2968336/
Abstract

The title compound, C(18)H(19)N(3)O(3), is a biologically active triazole derivative. The five-membered ring is oriented with respect to the six-membered rings at dihedral angles of 51.59 (4) and 61.37 (4)°. The crystal structure is stabilized by inter-molecular N-H⋯O hydrogen-bond inter-actions between centrosymmetrically related mol-ecules [the dihedral angle between the benzene rings is 47.44 (5)°].

摘要

标题化合物C(18)H(19)N(3)O(3)是一种具有生物活性的三唑衍生物。五元环相对于六元环的二面角为51.59 (4)°和61.37 (4)°。晶体结构通过中心对称相关分子之间的分子间N-H⋯O氢键相互作用得以稳定[苯环之间的二面角为47.44 (5)°]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72df/2968336/fc7cb5d6b5b2/e-65-0o429-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72df/2968336/4828d60e9733/e-65-0o429-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72df/2968336/fc7cb5d6b5b2/e-65-0o429-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72df/2968336/4828d60e9733/e-65-0o429-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72df/2968336/fc7cb5d6b5b2/e-65-0o429-fig2.jpg

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