2-（4-氟苯胺基）-3-（2-羟乙基）喹唑啉-4（3H）-酮
2-(4-Fluoro-anilino)-3-(2-hydroxy-ethyl)quinazolin-4(3H)-one.
作者信息
Zhang Qian, Jiao Yuan-Hong, Liu Bin, Chen Xue-Mei, Ruan Min, Xu Ling-Hua
机构信息
School of Chemistry and Material Engineering, Huangshi Institute of Technology, Huangshi 435003, People's Republic of China.
出版信息
Acta Crystallogr Sect E Struct Rep Online. 2009 Feb 28;65(Pt 3):o638. doi: 10.1107/S1600536809006254.
Abstract
The mol-ecular and crystal structures of the title compound, C(16)H(14)FN(3)O(2), are stabilized by intra-molecular N-H⋯O and inter-molecular O-H⋯O hydrogen bonds. The existence of non-classical intra-molecular C-H⋯N hydrogen bonds provides a dihedral angle between the fluoro-substituted benzene and pyrimidinone rings of 7.9 (1)°.
摘要
标题化合物C(16)H(14)FN(3)O(2)的分子结构和晶体结构通过分子内N-H⋯O和分子间O-H⋯O氢键得以稳定。非经典分子内C-H⋯N氢键的存在使得氟取代苯环与嘧啶酮环之间的二面角为7.9 (1)°。
Zotero 插件