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3-(2-羟乙基)-2-(对甲苯基氨基)-喹唑啉-4(3H)-酮

3-(2-Hydroxy-ethyl)-2-(p-tolyl-amino)-quinazolin-4(3H)-one.

作者信息

Zhang Gui-Fu, Ma Zuan, Yang Xu-Hong

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2008 Dec 6;65(Pt 1):o34-5. doi: 10.1107/S1600536808040440.

DOI:10.1107/S1600536808040440
PMID:21581677
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2967952/
Abstract

In the title compound, C(17)H(17)N(3)O(2), the quinazolinone ring system is essentially planar. The benzene ring is twisted with respect to it by a dihedral angle of 32.7 (5)°. The mol-ecular conformation is stabilized by an N-H⋯O hydrogen bond, and the crystal structure is stabilized by inter-molecular O-H⋯N inter-actions.

摘要

在标题化合物C(17)H(17)N(3)O(2)中，喹唑啉酮环系基本呈平面状。苯环相对于它扭转的二面角为32.7 (5)°。分子构象通过N-H⋯O氢键得以稳定，晶体结构则通过分子间O-H⋯N相互作用得以稳定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba9/2967952/9d2c9c9cb304/e-65-00o34-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba9/2967952/4a5f534c1bd3/e-65-00o34-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba9/2967952/9d2c9c9cb304/e-65-00o34-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba9/2967952/4a5f534c1bd3/e-65-00o34-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba9/2967952/9d2c9c9cb304/e-65-00o34-fig2.jpg

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