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(4S,5S)-2-(2-溴苯基)-1,3-二氧戊环-4,5-二甲酰胺

(4S,5S)-2-(2-Bromo-phen-yl)-1,3-dioxolane-4,5-dicarboxamide.

作者信息

Liu Hua-Quan, Wang De-Cai, Xu Wei, Yang Zheng, Gai Tao

机构信息

State Key Laboratory of Materials-Oriented Chemical Engineering, College of Life Science and Pharmaceutical Engineering, Nanjing University of Technology, Xinmofan Road No. 5 Nanjing, Nanjing 210009, People's Republic of China.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2009 Mar 25;65(Pt 4):o841. doi: 10.1107/S1600536809010009.

DOI:10.1107/S1600536809010009
PMID:21582560
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2969105/
Abstract

The asymmetric unit of the title compound, C(11)H(11)BrN(2)O(4), contains two crystallographically independent mol-ecules in which the bromo-phenyl rings are oriented at dihedral angles of 39.28 (3)°. The dioxolane rings adopt envelope conformations. Intra-molecular N-H⋯O hydrogen bonds result in the formation of four five-membered rings, having planar and envelope conformations. In the crystal structure, inter-molecular N-H⋯O hydrogen bonds link mol-ecules into chains along the b axis, forming R(2) (2)(8) ring motifs.

摘要

标题化合物C(11)H(11)BrN(2)O(4)的不对称单元包含两个晶体学独立的分子，其中溴苯环以39.28 (3)°的二面角取向。二氧戊环采取信封式构象。分子内N-H⋯O氢键导致形成四个具有平面和信封式构象的五元环。在晶体结构中，分子间N-H⋯O氢键将分子沿b轴连接成链，形成R(2) (2)(8)环基序。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d06/2969105/c58e0a690fa5/e-65-0o841-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d06/2969105/842ffbcbdaa2/e-65-0o841-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d06/2969105/c58e0a690fa5/e-65-0o841-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d06/2969105/842ffbcbdaa2/e-65-0o841-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d06/2969105/c58e0a690fa5/e-65-0o841-fig2.jpg

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