用于测量拓扑异构酶活性的体外测定法。 - Suppr

Suppr

超能文献

In vitro assays used to measure the activity of topoisomerases.

作者信息

Barrett J F, Sutcliffe J A, Gootz T D

机构信息

Department of Immunology and Infectious Diseases, Pfizer Central Research, Groton, Connecticut 06340.

出版信息

Antimicrob Agents Chemother. 1990 Jan;34(1):1-7. doi: 10.1128/AAC.34.1.1.

DOI:10.1128/AAC.34.1.1

PMID:2158270

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC171509/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47d8/171509/7c96c5522205/aac00057-0034-a.jpg

相似文献

In vitro assays used to measure the activity of topoisomerases.用于测量拓扑异构酶活性的体外测定法。

Antimicrob Agents Chemother. 1990 Jan;34(1):1-7. doi: 10.1128/AAC.34.1.1.

Biochemical characteristics and physiological significance of major DNA topoisomerases.主要DNA拓扑异构酶的生化特性及生理意义

Antimicrob Agents Chemother. 1989 Dec;33(12):2027-33. doi: 10.1128/AAC.33.12.2027.

Biochemistry of bacterial type I DNA topoisomerases.

Adv Pharmacol. 1994;29A:21-37. doi: 10.1016/s1054-3589(08)60538-4.

DNA topoisomerases.DNA拓扑异构酶

Cell. 1980 Nov;22(2 Pt 2):327-8. doi: 10.1016/0092-8674(80)90341-4.

Separation and functional analysis of eukaryotic DNA topoisomerases by chromatography and electrophoresis.通过色谱法和电泳法对真核生物DNA拓扑异构酶进行分离和功能分析。

J Chromatogr B Biomed Appl. 1996 Sep 20;684(1-2):307-21. doi: 10.1016/0378-4347(96)00152-1.

Analysis of eukaryotic DNA topoisomerases and topoisomerase-directed drug effects.真核生物DNA拓扑异构酶及拓扑异构酶导向药物效应分析。

Eur J Clin Chem Clin Biochem. 1996 Nov;34(11):873-88.

Topoisomerase assays.

Curr Protoc Pharmacol. 2001 May;Chapter 3:Unit3.3. doi: 10.1002/0471141755.ph0303s00.

Archaebacterial reverse gyrase cleavage-site specificity is similar to that of eubacterial DNA topoisomerases I.古细菌反向回旋酶的切割位点特异性与真细菌DNA拓扑异构酶I的相似。

Nucleic Acids Res. 1990 May 11;18(9):2801-5. doi: 10.1093/nar/18.9.2801.

Assaying DNA topoisomerase I relaxation activity.

Methods Mol Biol. 2001;95:1-11. doi: 10.1385/1-59259-057-8:1.

Studies on DNA polymerases and topoisomerases in archaebacteria.古细菌中DNA聚合酶和拓扑异构酶的研究。

Can J Microbiol. 1989 Jan;35(1):228-33. doi: 10.1139/m89-035.

引用本文的文献

Multi-Function of a New Bioactive Secondary Metabolite Derived from Endophytic Fungus of .一种新型生物活性次生代谢产物的多功能性，来源于. 的内生真菌。

J Microbiol Biotechnol. 2023 Jun 28;33(6):806-822. doi: 10.4014/jmb.2206.06010. Epub 2022 Dec 27.

A "Double-Edged" Scaffold: Antitumor Power within the Antibacterial Quinolone.一种“双刃剑”支架：抗菌喹诺酮类药物中的抗肿瘤作用

Curr Med Chem. 2016;23(6):520-77. doi: 10.2174/0929867323666151223095839.

The topoisomerase II inhibitor voreloxin causes cell cycle arrest and apoptosis in myeloid leukemia cells and acts in synergy with cytarabine.拓扑异构酶 II 抑制剂沃利替尼可引起髓系白血病细胞的细胞周期停滞和凋亡，并与阿糖胞苷协同作用。

Haematologica. 2011 Mar;96(3):393-9. doi: 10.3324/haematol.2010.032680. Epub 2010 Dec 6.

Topoisomerase I inhibitors and drug resistance.拓扑异构酶 I 抑制剂与耐药性。

Cytotechnology. 1998 Sep;27(1-3):149-64. doi: 10.1023/A:1008008719699.

Dual targeting of topoisomerase IV and gyrase to reduce mutant selection: direct testing of the paradigm by using WCK-1734, a new fluoroquinolone, and ciprofloxacin.双重靶向拓扑异构酶IV和回旋酶以减少突变选择：使用新型氟喹诺酮类药物WCK-1734和环丙沙星对该范例进行直接测试。

Antimicrob Agents Chemother. 2005 May;49(5):1949-56. doi: 10.1128/AAC.49.5.1949-1956.2005.

Quinolone-binding pocket of DNA gyrase: role of GyrB.DNA 回旋酶的喹诺酮结合口袋：GyrB 的作用

Antimicrob Agents Chemother. 2002 Jun;46(6):1805-15. doi: 10.1128/AAC.46.6.1805-1815.2002.

Stereo (C7)-dependent topoisomerase II inhibition and tumor growth suppression by a new quinolone, BO-2367.新型喹诺酮类药物BO - 2367对立体（C7）依赖性拓扑异构酶II的抑制作用及肿瘤生长抑制作用

Jpn J Cancer Res. 1993 Jul;84(7):800-6. doi: 10.1111/j.1349-7006.1993.tb02047.x.

Topoisomerase I in multiple drug resistance.多药耐药中的拓扑异构酶I

Cytotechnology. 1993;12(1-3):127-35. doi: 10.1007/BF00744661.

CP-115,953 stimulates cytokine production by lymphocytes.CP - 115,953刺激淋巴细胞产生细胞因子。

Antimicrob Agents Chemother. 1995 Feb;39(2):476-83. doi: 10.1128/AAC.39.2.476.

Inhibitory effects of quinolone antibacterial agents on eucaryotic topoisomerases and related test systems.喹诺酮类抗菌剂对真核拓扑异构酶的抑制作用及相关测试系统

Antimicrob Agents Chemother. 1990 Jan;34(1):8-12. doi: 10.1128/AAC.34.1.8.

本文引用的文献

Fluorometric method for rapid detection of DNA strand breaks in human white blood cells produced by low doses of radiation.低剂量辐射致人类白细胞DNA链断裂的快速荧光检测方法

Cancer Res. 1981 May;41(5):1889-92.

Inhibition of the DNA catenation activity of type II topoisomerase by VP16-213 and VM26.VP16 - 213和VM26对II型拓扑异构酶DNA连环化活性的抑制作用。

Biochem Biophys Res Commun. 1984 Jul 18;122(1):165-70. doi: 10.1016/0006-291x(84)90454-6.

HMG17 protein facilitates the DNA catenation reaction catalyzed by DNA topoisomerases.HMG17蛋白促进由DNA拓扑异构酶催化的DNA连环反应。

Arch Biochem Biophys. 1984 May 15;231(1):169-74. doi: 10.1016/0003-9861(84)90374-6.

Rapid detection and isolation of covalent DNA/protein complexes: application to topoisomerase I and II.共价DNA/蛋白质复合物的快速检测与分离：应用于拓扑异构酶I和II

EMBO J. 1984 Mar;3(3):671-6. doi: 10.1002/j.1460-2075.1984.tb01865.x.

Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide.抗肿瘤药物作用机制：4'-（9-吖啶基氨基）-间甲氧基甲磺酰苯胺对哺乳动物DNA拓扑异构酶II在DNA上的毒害作用。

Proc Natl Acad Sci U S A. 1984 Mar;81(5):1361-5. doi: 10.1073/pnas.81.5.1361.

Potent catenation of supercoiled and gapped DNA circles by topoisomerase I in the presence of a hydrophilic polymer.在亲水性聚合物存在的情况下，拓扑异构酶I对超螺旋和缺口DNA环进行有效的连环化作用。

J Biol Chem. 1984 Apr 10;259(7):4576-81.

Inhibition of the reactions catalysed by a type I topoisomerase and catenating enzyme of Trypanosoma cruzi by DNA-intercalating drugs. Preferential inhibition of the catenating reaction.

EMBO J. 1984 Jan;3(1):11-6. doi: 10.1002/j.1460-2075.1984.tb01754.x.

Yeast DNA topoisomerase II is encoded by a single-copy, essential gene.酵母DNA拓扑异构酶II由一个单拷贝的必需基因编码。

Cell. 1984 Apr;36(4):1073-80. doi: 10.1016/0092-8674(84)90057-6.

DNA topoisomerases--enzymes that catalyse the breaking and rejoining of DNA.DNA拓扑异构酶——催化DNA断裂和重新连接的酶。

CRC Crit Rev Biochem. 1983;15(1):1-24. doi: 10.3109/10409238309102799.

Cleavage of DNA by mammalian DNA topoisomerase II.哺乳动物DNA拓扑异构酶II对DNA的切割

J Biol Chem. 1983 Dec 25;258(24):15365-70.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验