• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

（±）-顺式-异丙基 4-（1,1,1,3,3,3-六氟丙-2-基氧基）-1-羟基-3-甲基-2-（丙-1-炔基）环戊-2-烯羧酸酯

(±)-syn-Isopropyl 4-(1,1,1,3,3,3-hexa-fluoro-propan-2-yl-oxy)-1-hydr-oxy-3-methyl-2-(prop-1-yn-yl)cyclo-pent-2-ene-carboxyl-ate.

作者信息

Gille Annika, Schürmann Markus, Preut Hans, Hiersemann Martin

机构信息

Fakultät Chemie, Technische Universität Dortmund, Otto-Hahn-Strasse 6, 44221 Dortmund, Germany.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2009 Jun 20;65(Pt 7):o1660. doi: 10.1107/S1600536809023162.

DOI:10.1107/S1600536809023162
PMID:21582922
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2969198/
Abstract

The title compound, C(16)H(18)F(6)O(4), was obtained through an unprecedented one-pot reaction sequence involving a Gosteli-Claisen rearrangement and a cyclo-isomerization. The constitution and relative configuration were determined by single-crystal X-ray diffraction analysis. In the crystal, mol-ecules are connected via O-H ⋯ O hydrogen bonds.

摘要

标题化合物C(16)H(18)F(6)O(4)是通过一个前所未有的一锅反应序列得到的，该序列涉及戈斯特利-克莱森重排和环异构化反应。其结构和相对构型通过单晶X射线衍射分析确定。在晶体中，分子通过O-H⋯O氢键相连。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c773/2969198/7e6c89db67dd/e-65-o1660-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c773/2969198/7e6c89db67dd/e-65-o1660-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c773/2969198/7e6c89db67dd/e-65-o1660-fig1.jpg

相似文献

1
(±)-syn-Isopropyl 4-(1,1,1,3,3,3-hexa-fluoro-propan-2-yl-oxy)-1-hydr-oxy-3-methyl-2-(prop-1-yn-yl)cyclo-pent-2-ene-carboxyl-ate.（±）-顺式-异丙基 4-（1,1,1,3,3,3-六氟丙-2-基氧基）-1-羟基-3-甲基-2-（丙-1-炔基）环戊-2-烯羧酸酯
Acta Crystallogr Sect E Struct Rep Online. 2009 Jun 20;65(Pt 7):o1660. doi: 10.1107/S1600536809023162.
2
(3R,4R,5S)-4-Hydr-oxy-3-methyl-5-[(2S,3R)-3-methyl-pent-4-en-2-yl]-4,5-dihydro-furan-2(3H)-one.(3R,4R,5S)-4-羟基-3-甲基-5-[(2S,3R)-3-甲基-戊-4-烯-2-基]-4,5-二氢呋喃-2(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2009 Nov 28;65(Pt 12):o3274. doi: 10.1107/S1600536809050399.
3
Preaustinoid A: a meroterpene produced by Penicillium sp.
Acta Crystallogr Sect E Struct Rep Online. 2009 Jan 8;65(Pt 2):o221. doi: 10.1107/S1600536808043481.
4
(3S,4S,5R)-4-Hydr-oxy-3-methyl-5-[(2S,3R)-3-methyl-pent-4-en-2-yl]-4,5-dihydro-furan-2(3H)-one.（3S，4S，5R）-4-羟基-3-甲基-5-[(2S，3R)-3-甲基戊-4-烯-2-基]-4,5-二氢呋喃-2(3H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2008 Dec 17;65(Pt 1):o154. doi: 10.1107/S1600536808042414.
5
N-[(R)-(2-Chloro-phen-yl)(cyclo-pent-yl)meth-yl]-N-[(R)-(2-hydr-oxy-5-methyl-phen-yl)(phen-yl)meth-yl]acetamide.N-[(R)-(2-氯苯基)(环戊基)甲基]-N-[(R)-(2-羟基-5-甲基苯基)(苯基)甲基]乙酰胺
Acta Crystallogr Sect E Struct Rep Online. 2009 Oct 31;65(Pt 11):o2948. doi: 10.1107/S1600536809044808.
6
2-Hydr-oxy-16-[(E)-4-hydr-oxy-3-methoxy-benzyl-idene]-13-(4-hydr-oxy-3-methoxy-phen-yl)-11-methyl-1,11-diaza-penta-cyclo-[12.3.1.0.0.0]octa-deca-3(8),4,6-triene-9,15-dione.2-羟基-16-[(E)-4-羟基-3-甲氧基亚苄基]-13-(4-羟基-3-甲氧基苯基)-11-甲基-1,11-二氮杂五环-[12.3.1.0.0.0]十八碳-3(8),4,6-三烯-9,15-二酮
Acta Crystallogr Sect E Struct Rep Online. 2010 May 15;66(Pt 6):o1370-1. doi: 10.1107/S1600536810017216.
7
tert-Butyl N-hydr-oxy-N-[(1S*,2R*)-2-(1-naphth-yl)cyclo-pent-3-en-1-yl]carbamate.N-羟基-N-[(1S*,2R*)-2-(1-萘基)环戊-3-烯-1-基]叔丁基氨基甲酸酯
Acta Crystallogr Sect E Struct Rep Online. 2009 Jun 6;65(Pt 7):o1481. doi: 10.1107/S1600536809020315.
8
A triclinic polymorph of (E)-2-(1-hy-droxy-3-phenyl-prop-2-en-1-yl-idene)-4,5-dimeth-oxy-cyclo-pent-4-ene-1,3-dione.（E）-2-（1-羟基-3-苯基-丙-2-烯-1-亚基）-4,5-二甲氧基-环戊-4-烯-1,3-二酮的三斜多晶型物。
Acta Crystallogr Sect E Struct Rep Online. 2012 Feb 1;68(Pt 2):o453. doi: 10.1107/S1600536812001043. Epub 2012 Jan 18.
9
The cocrystal 2-hydr-oxy-4-methyl-N-propanoylbenzohydrazide-2-hydr-oxy-N-(2-hydr-oxy-4-methyl-benzo-yl)-6-methyl-benzohydrazide (2/1).共晶体2-羟基-4-甲基-N-丙酰基苯甲酰肼-2-羟基-N-(2-羟基-4-甲基苯甲酰基)-6-甲基苯甲酰肼(2/1)
Acta Crystallogr Sect E Struct Rep Online. 2008 Oct 18;64(Pt 11):o2144. doi: 10.1107/S1600536808033515.
10
Bis(dimethyl-ammonium) 3,3'-dicarb-oxy-5,5'-(5,7,12,14-tetra-oxo-6,13-diaza-tetra-cyclo-[6.6.2.0(4,16).0(11,15)]hexa-deca-1,3,8,10,15-penta-ene-6,13-di-yl)dibenzoate dihydrate.二水合双（二甲基铵）3,3'-二羧基-5,5'-（5,7,12,14-四氧代-6,13-二氮杂四环-[6.6.2.0(4,16).0(11,15)]十六碳-1,3,8,10,15-五烯-6,13-二亚基）二苯甲酸酯
Acta Crystallogr Sect E Struct Rep Online. 2012 Jul 1;68(Pt 7):o2174-5. doi: 10.1107/S1600536812025470. Epub 2012 Jun 23.

引用本文的文献

1
Biomolecular chemistry of isopropyl fibrates.异丙醇纤维酸的生物分子化学。
J Pharm Sci. 2012 Apr;101(4):1555-69. doi: 10.1002/jps.23040. Epub 2012 Jan 13.

本文引用的文献

1
Structure validation in chemical crystallography.化学晶体学中的结构验证
Acta Crystallogr D Biol Crystallogr. 2009 Feb;65(Pt 2):148-55. doi: 10.1107/S090744490804362X. Epub 2009 Jan 20.
2
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
3
[New synthesis of pyrrolnitrin antibiotics].
Helv Chim Acta. 1972 Mar 10;55(2):451-60. doi: 10.1002/hlca.19720550216.