3-(1-乙基-1H-吡咯-2-甲酰胺基)丙酸一水合物
3-(1-Ethyl-1H-pyrrole-2-carboxamido)propionic acid monohydrate.
作者信息
Li Dong Dong, Tang Gui Hong, Zeng Xiang Chao, Huang Gang, Xu Xing Yan
机构信息
Department of Chemistry, Jinan University, Guangzhou, Guangdong, 510632, People's Republic of China.
出版信息
Acta Crystallogr Sect E Struct Rep Online. 2009 Jul 15;65(Pt 8):o1865. doi: 10.1107/S1600536809026749.
Abstract
The title compound, C(10)H(14)N(2)O(3)·H(2)O, was synthesized by alkyl-ation of methyl 3-(1H-pyrrole-2-carboxamido)-propion-ate with ethyl bromide, followed by saponification and acidification. In the crystal structure, inter-molecular O-H⋯O and N-H⋯O hydrogen bonds link the mol-ecules, forming layers parallel to the ac plane.
摘要
标题化合物C(10)H(14)N(2)O(3)·H(2)O是通过3-(1H-吡咯-2-甲酰胺基)丙酸甲酯与溴乙烷进行烷基化反应，随后进行皂化和酸化反应合成的。在晶体结构中，分子间的O-H⋯O和N-H⋯O氢键将分子连接起来，形成平行于ac平面的层。
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