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2-溴-N-(2-氯苯基)乙酰胺

2-Bromo-N-(2-chloro-phen-yl)acetamide.

作者信息

Gowda B Thimme, Foro Sabine, Suchetan P A, Fuess Hartmut, Terao Hiromitsu

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2009 Jul 25;65(Pt 8):o1998. doi: 10.1107/S1600536809028918.

DOI:10.1107/S1600536809028918
PMID:21583670
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2977351/
Abstract

The conformation of the N-H bond in the structure of the title compound, C(8)H(7)BrClNO, is syn to the 2-chloro substituent in the aniline ring and anti to both the C=O and C-Br bonds in the side chain, similar to that observed in 2-chloro-N-(2-chloro-phen-yl)acetamide. In the crystal, mol-ecules are linked into chains along the a axis by N-H⋯O hydrogen bonds. These chains are in turn linked into pairs, in the form of columns, through much weaker C-H⋯Cl and Br⋯Br [4.3027 (3) Å] inter-actions.

摘要

标题化合物C(8)H(7)BrClNO结构中N - H键的构象与苯胺环上的2 - 氯取代基呈顺式，与侧链中的C=O和C - Br键均呈反式，这与在2 - 氯 - N - (2 - 氯 - 苯基)乙酰胺中观察到的情况类似。在晶体中，分子通过N - H⋯O氢键沿a轴连接成链。这些链又通过弱得多的C - H⋯Cl和Br⋯Br [4.3027 (3) Å]相互作用成对连接成柱状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b4/2977351/f44b00ee4267/e-65-o1998-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b4/2977351/01195644fbe2/e-65-o1998-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b4/2977351/f44b00ee4267/e-65-o1998-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b4/2977351/01195644fbe2/e-65-o1998-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/45b4/2977351/f44b00ee4267/e-65-o1998-fig2.jpg

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