Zhou Zhongzhen, You Wenwei, Tang Zhongkun, Zhao Peiliang
School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, People's Republic of China.
Acta Crystallogr Sect E Struct Rep Online. 2009 Jul 29;65(Pt 8):o2015. doi: 10.1107/S1600536809028815.
In the crystal structure of the title compound, C(25)H(30)N(2)O(4), the steric size of the tert-butyl group causes the 3,5-dimethyl-phenyl ring to adopt a transoid geometry with respect to the N-C(O) bond. The six-membered heterocyclic ring is disordered over two sites, with occupancies of 0.553 (4) and 0.447 (4). Intra-molecular C-H⋯O inter-actions are present. In the crystal, mol-ecules are linked by inter-molecular N-H⋯O and C-H⋯O hydrogen bonds.
在标题化合物C(25)H(30)N(2)O(4)的晶体结构中,叔丁基的空间大小导致3,5-二甲基苯基环相对于N-C(O)键采取反式构象。六元杂环在两个位置上无序,占有率分别为0.553 (4)和0.447 (4)。存在分子内C-H⋯O相互作用。在晶体中,分子通过分子间N-H⋯O和C-H⋯O氢键相连。