• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

N'-叔丁基-N'-(3,5-二甲基苯甲酰基)-2,2-二甲基-4-氧代苯并二氢吡喃-6-碳酰肼

N'-tert-Butyl-N'-(3,5-dimethyl-benzo-yl)-2,2-dimethyl-4-oxochroman-6-carbo-hydrazide.

作者信息

Zhou Zhongzhen, You Wenwei, Tang Zhongkun, Zhao Peiliang

机构信息

School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, People's Republic of China.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2009 Jul 29;65(Pt 8):o2015. doi: 10.1107/S1600536809028815.

DOI:10.1107/S1600536809028815
PMID:21583686
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2977281/
Abstract

In the crystal structure of the title compound, C(25)H(30)N(2)O(4), the steric size of the tert-butyl group causes the 3,5-dimethyl-phenyl ring to adopt a transoid geometry with respect to the N-C(O) bond. The six-membered heterocyclic ring is disordered over two sites, with occupancies of 0.553 (4) and 0.447 (4). Intra-molecular C-H⋯O inter-actions are present. In the crystal, mol-ecules are linked by inter-molecular N-H⋯O and C-H⋯O hydrogen bonds.

摘要

在标题化合物C(25)H(30)N(2)O(4)的晶体结构中，叔丁基的空间大小导致3,5-二甲基苯基环相对于N-C(O)键采取反式构象。六元杂环在两个位置上无序，占有率分别为0.553 (4)和0.447 (4)。存在分子内C-H⋯O相互作用。在晶体中，分子通过分子间N-H⋯O和C-H⋯O氢键相连。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12be/2977281/187ac5ee1913/e-65-o2015-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12be/2977281/801fa72b505d/e-65-o2015-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12be/2977281/187ac5ee1913/e-65-o2015-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12be/2977281/801fa72b505d/e-65-o2015-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12be/2977281/187ac5ee1913/e-65-o2015-fig2.jpg

相似文献

1
N'-tert-Butyl-N'-(3,5-dimethyl-benzo-yl)-2,2-dimethyl-4-oxochroman-6-carbo-hydrazide.N'-叔丁基-N'-(3,5-二甲基苯甲酰基)-2,2-二甲基-4-氧代苯并二氢吡喃-6-碳酰肼
Acta Crystallogr Sect E Struct Rep Online. 2009 Jul 29;65(Pt 8):o2015. doi: 10.1107/S1600536809028815.
2
3-Hydr-oxy-N'-[(Z)-(5-methyl-2-fur-yl)methyl-idene]naphthalene-2-carbo-hydrazide.3-羟基-N'-[(Z)-(5-甲基-2-呋喃基)亚甲基]萘-2-碳酰肼
Acta Crystallogr Sect E Struct Rep Online. 2009 Oct 23;65(Pt 11):o2845-6. doi: 10.1107/S1600536809043141.
3
4-[(Z)-(2-Eth-oxy-4-oxochroman-3-yl-idene)methyl-amino]benzene-sulfonamide monohydrate.4-[(Z)-(2-乙氧基-4-氧代苯并二氢吡喃-3-亚基)甲基氨基]苯磺酰胺一水合物
Acta Crystallogr Sect E Struct Rep Online. 2009 Jul 11;65(Pt 8):o1818-9. doi: 10.1107/S1600536809026154.
4
N'-[(E)-1-Phenyl-ethyl-idene]benzo-hydrazide.N'-[(E)-1-苯基-亚乙基]苯甲酰肼
Acta Crystallogr Sect E Struct Rep Online. 2008 Sep 20;64(Pt 10):o1961-2. doi: 10.1107/S1600536808029218.
5
N'-[(1E)-3-Bromo-5-chloro-2-hy-droxy-benzyl-idene]-4-tert-butyl-benzo-hydrazide ethanol monosolvate.N'-[(1E)-3-溴-5-氯-2-羟基亚苄基]-4-叔丁基苯甲酰肼乙醇单溶剂合物
Acta Crystallogr Sect E Struct Rep Online. 2011 Nov;67(Pt 11):o2857. doi: 10.1107/S160053681104027X. Epub 2011 Oct 5.
6
N'-[(Z)-4-(Dimethyl-amino)benzyl-idene]-4-nitro-benzohydrazide mono-hydrate.N'-[(Z)-4-(二甲基氨基)亚苄基]-4-硝基苯甲酰肼一水合物
Acta Crystallogr Sect E Struct Rep Online. 2008 Sep 13;64(Pt 10):o1907-8. doi: 10.1107/S1600536808028328.
7
N'-[1-(2-Amino-phen-yl)ethyl-idene]benzo-hydrazide.N'-[1-(2-氨基苯基)亚乙基]苯甲酰肼
Acta Crystallogr Sect E Struct Rep Online. 2010 Apr 24;66(Pt 5):o1172. doi: 10.1107/S1600536810010937.
8
Crystal structure of ethyl 2-(2-{1-[N-(4-bromo-phen-yl)-2-oxo-2-phenyl-acetamido]-2-tert-butyl-amino-2-oxo-ethyl}-1H-pyrrol-1-yl)acetate.2-(2-{1-[N-(4-溴苯基)-2-氧代-2-苯基乙酰胺基]-2-叔丁基氨基-2-氧代乙基}-1H-吡咯-1-基)乙酸乙酯的晶体结构
Acta Crystallogr E Crystallogr Commun. 2015 Dec 12;71(Pt 12):o1049-50. doi: 10.1107/S2056989015023592. eCollection 2015 Dec 1.
9
2-[4-(2-Methyl-prop-yl)phen-yl]-N'-[(E)-1-phenyl-ethyl-idene]propane-hydrazide.2-[4-(2-甲基丙基)苯基]-N'-[(E)-1-苯基亚乙基]丙烷酰肼
Acta Crystallogr Sect E Struct Rep Online. 2008 Nov 20;64(Pt 12):o2377. doi: 10.1107/S1600536808036817.
10
N'-[1-(2,4-Dioxo-3,4-dihydro-2H-1-benzopyran-3-yl-idene)eth-yl]thiophene-2-carbo-hydrazide.N'-[1-(2,4-二氧代-3,4-二氢-2H-1-苯并吡喃-3-亚基)乙基]噻吩-2-碳酰肼
Acta Crystallogr Sect E Struct Rep Online. 2011 Apr 1;67(Pt 4):o1014. doi: 10.1107/S1600536811010907. Epub 2011 Mar 31.

本文引用的文献

1
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
2
Synthesis and insecticidal evaluation of novel N'-tert-butyl-N'-substitutedbenzoyl-N-5-chloro-6-chromanecarbohydrazide derivatives.新型N'-叔丁基-N'-取代苯甲酰基-N-5-氯-6-色满甲酰肼衍生物的合成及杀虫活性评价
Bioorg Med Chem. 2008 Jan 1;16(1):488-94. doi: 10.1016/j.bmc.2007.09.018. Epub 2007 Sep 14.
3
Synthesis and insecticidal activity of chromanone and chromone analogues of diacylhydrazines.
二酰肼类色满酮和色酮类似物的合成及其杀虫活性
Bioorg Med Chem. 2007 Mar 1;15(5):1888-95. doi: 10.1016/j.bmc.2007.01.008. Epub 2007 Jan 11.
4
Synthesis and insecticidal activity of benzoheterocyclic analogues of N'-benzoyl-N-(tert-butyl)benzohydrazide: Part 3. Modification of N-tert-butylhydrazine moiety.N'-苯甲酰基-N-(叔丁基)苯甲酰肼的苯并杂环类似物的合成与杀虫活性：第3部分。N-叔丁基肼部分的修饰。
Pest Manag Sci. 2003 Jan;59(1):49-57. doi: 10.1002/ps.606.