11β,17,21 - 三羟基 - 6α - 甲基 - 3,20 - 二氧代孕甾 - 1,4 - 二烯 - 21 - 基3 - 羧基丙酸酯
11β,17,21-Trihydr-oxy-6α-methyl-3,20-dioxopregna-1,4-dien-21-yl 3-carboxy-propionate.
作者信息
An Hui-Mei, Gong Ning-Bo, Lu Yang
机构信息
Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, 1 Xiannong tan street, Beijing 100050, People's Republic of China.
出版信息
Acta Crystallogr Sect E Struct Rep Online. 2009 Apr 8;65(Pt 5):o987. doi: 10.1107/S1600536809011969.
The mol-ecule of the title compound, C(26)H(34)O(8), a prednisolone derivative, contains three six-membered rings (A, B and C) and one five-membered ring (D). Ring A is planar and rings B and C adopt chair conformations, while ring D adopts an envelope conformation with the C atom bonded to the methyl group at the flap. The crystal structure is stabilized by intermolecular O-H⋯O hydrogen bonds.
标题化合物C(26)H(34)O(8)（一种泼尼松龙衍生物）的分子包含三个六元环（A、B和C）和一个五元环（D）。环A是平面的，环B和C采取椅式构象，而环D采取信封式构象，其中在翼片处与甲基相连的C原子处于该构象。晶体结构通过分子间O-H⋯O氢键得以稳定。
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