S.K. MATTOO, M.D., Associate Professor, Department of Postgraduate Institute of Medical Education and Research, Chandigarh-160 012.
Indian J Psychiatry. 1997 Oct;39(4):294-9.
In 47 subjects having alcohol dependence syndrome, the progression of alcohol related milestones was studied in terms of age-at-onset of each milestone. The findings revealed a definable progression with three phases. The early phase, characterized by the absence of any problem, ended with the use of 1/4th bottle of spirit a day, more than once-a-week. The middle phase began with daily drinking, ended with the use of 1 bottle of spirit a day, and was characterized mainly by social problems. The late phase began with the onset of morning drinking, and was characterized by the addition of physical problems. These findings support the earlier research suggesting a definable progression of alcoholism. However the physiology identified by the present study is unlike that reported by some of the earlier research.
在 47 名患有酒精依赖综合征的受试者中，根据每个里程碑的发病年龄，研究了与酒精相关的里程碑的进展情况。研究结果显示，这一过程具有三个阶段的可定义进展。早期阶段，特征是没有任何问题，以每天使用四分之一瓶烈酒，每周不止一次结束。中期阶段从每天饮酒开始，以每天使用一瓶烈酒结束，主要以社会问题为特征。晚期阶段以晨饮开始，以身体问题为特征。这些发现支持了早期研究提出的酒精中毒的可定义进展。然而，本研究确定的生理学与一些早期研究报告的不同。
