直接从 Herz 化合物合成 2-氨基苯并噻唑。
A straightforward synthesis of 2-aminobenzothiazoles from Herz compounds.
机构信息
Laboratorio de Química Orgánica y Bioorgánica (L.O.B.O.), Dept. Química Orgánica e Inorgánica, Facultad de Veterinaria, Universidad de Extremadura, 10071, Cáceres, Spain.
出版信息
Org Biomol Chem. 2011 Jul 7;9(13):4850-5. doi: 10.1039/c1ob05398a. Epub 2011 May 16.
PMID:21584300
Abstract
2-Aminobenzothiazoles are readily synthesised from anilines, sulfur monochloride and isocyanides. The key step consists of an iodine-catalysed insertion of isocyanides into the S-S bond of hydrolysed Herz salts, with concomitant extrusion of sulfur monoxide.
摘要
2-氨基苯并噻唑可由苯胺、一氯化硫和异氰化物容易地合成。关键步骤是在碘催化下异氰化物插入水解 Herz 盐的 S-S 键中，同时释放出一氧化硫。
Zotero 插件