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非结直肠癌肝转移的动脉治疗(从化疗栓塞到放射性栓塞)。

Arterial therapies of non-colorectal cancer metastases to the liver (from chemoembolization to radioembolization).

作者信息

Hoffmann Ralf Thorsten, Paprottka P, Jakobs T F, Trumm C G, Reiser M F

机构信息

Institute and Clinic for Radiology, University Hospital of Dresden, Fetscherstr. 74, 01307, Dresden, Germany.

出版信息

Abdom Imaging. 2011 Dec;36(6):671-6. doi: 10.1007/s00261-011-9753-6.

Abstract

Treatment of primary and secondary hepatic malignancies with transarterial chemoembolization (TACE) represents an essential component of interventional oncology known for many years and performed by many interventional radiologists first in primary liver tumors and nowadays even in metastases of different origins. Radioembolization (RE) has been introduced to the clinical arsenal of cytoreductive modalities in recent years. There is growing evidence for efficiency in liver tumors of various entities, with the most prominent ones being hepatocellular carcinoma, colorectal cancer, and neuroendocrine tumors. Hepatic metastases of other tumor entities (breast cancer, malignant melanoma, and pancreatic cancer) are treatment-sensitive. This article focuses on procedural and technical aspects for selection, preparation, and performance of treatment as well as the results in metastatic breast cancer, neuroendocrine tumors, melanoma, and pancreatic cancer giving an overview of the results after RE, transarterial embolization, or TACE.

摘要

经动脉化疗栓塞术(TACE)治疗原发性和继发性肝脏恶性肿瘤是介入肿瘤学的重要组成部分,多年来已为众多介入放射科医生所熟知,最初用于原发性肝癌,如今甚至用于不同来源的肝转移瘤。放射性栓塞术(RE)近年来已被引入细胞减灭治疗手段的临床武器库。越来越多的证据表明其对各种实体肝脏肿瘤有效,其中最突出的是肝细胞癌、结直肠癌和神经内分泌肿瘤。其他肿瘤实体(乳腺癌、恶性黑色素瘤和胰腺癌)的肝转移瘤对治疗敏感。本文重点关注治疗选择、准备和实施的程序及技术方面,以及转移性乳腺癌、神经内分泌肿瘤、黑色素瘤和胰腺癌的治疗结果,概述放射性栓塞术、经动脉栓塞术或经动脉化疗栓塞术后的结果。

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