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二十世纪之交对脑瘫的认识与手术治疗:哈维·库欣早期涉足小儿神经外科领域。

The understanding and operative treatment of cerebral palsy at the turn of the twentieth century: Harvey Cushing's early forays into pediatric neurosurgery.

作者信息

Dmetrichuk Jennifer M, Pendleton Courtney, Ahn Edward S, Quiñones-Hinojosa Alfredo

机构信息

School of Medicine and Dentistry, University of Aberdeen, Scotland, UK.

出版信息

Childs Nerv Syst. 2011 Sep;27(9):1483-8. doi: 10.1007/s00381-011-1478-x. Epub 2011 May 17.

DOI:10.1007/s00381-011-1478-x
PMID:21584747
Abstract

INTRODUCTION

At the turn of the twentieth century, cerebral palsy and its treatment were not well understood, and a variety of treatment modalities were tested with only limited success.

MATERIAL AND METHODS

Following IRB approval and through the courtesy of the Alan Mason Chesney Archives, we reviewed the Johns Hopkins Hospital surgical files from 1896-1912. Eight patients who received a diagnosis consistent with cerebral palsy and were treated surgically by Dr. Cushing were selected for further analysis and are described here.

RESULTS

A total of eight patients underwent operative intervention for treatment of symptoms consistent with cerebral palsy. Of these, seven were male; the mean age was 4.9 years (range, 1.5 to 12). Five patients underwent decompressive craniotomies, one underwent tenotomies, one underwent transection of the spinal nerve roots, and one underwent primary transection of the spinal nerve roots with secondary tenotomies. Four representative cases are reported here.

CONCLUSIONS

Cushing's contributions to pediatric neuro-oncology have been previously described, but his endeavors in non-oncologic realms remain largely unknown. Although Cushing employed previously described operative approaches for the treatment of cerebral palsy, parents brought their children to him from across the nation, in an era when long distance travel was tedious, and a financial burden. These cases serve to emphasize Cushing's interest in improving patient quality of life, and his broad contributions to pediatric neurosurgery.

摘要

引言

在二十世纪之交,人们对脑瘫及其治疗方法了解甚少,各种治疗方式的试验效果有限。

材料与方法

经机构审查委员会(IRB)批准,并承蒙艾伦·梅森·切斯尼档案馆的协助,我们查阅了约翰·霍普金斯医院1896年至1912年的外科手术档案。挑选了八名被诊断为脑瘫且由库欣医生进行手术治疗的患者进行进一步分析,并在此进行描述。

结果

共有八名患者因与脑瘫相符的症状接受了手术干预。其中,七名是男性;平均年龄为4.9岁(范围为1.5至12岁)。五名患者接受了减压开颅手术,一名接受了肌腱切断术,一名接受了脊神经根切断术,一名接受了脊神经根初次切断术并辅以肌腱切断术。这里报告了四个代表性病例。

结论

库欣对小儿神经肿瘤学的贡献此前已有描述,但他在非肿瘤领域的努力在很大程度上仍不为人知。尽管库欣采用了先前描述的手术方法治疗脑瘫,但在长途旅行既乏味又负担沉重的那个时代,家长们仍从全国各地把孩子带到他这里。这些病例有助于强调库欣对改善患者生活质量的关注,以及他对小儿神经外科的广泛贡献。

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