Swenson C L, Kociba G J, Mathes L E, Hand P J, Neer C A, Hayes K A, Olsen R G
Department of Veterinary Pathobiology, College of Veterinary Medicine, Ohio State University, Columbus 43210.
J Am Vet Med Assoc. 1990 Apr 1;196(7):1049-52.
Feline leukemia virus status and antibody titer to feline oncornavirus-associated cell membrane antigen (FOCMA) were determined on plasma from 183 outpatient cats and 61 cats from 2 closed, FeLV-positive, multiple-cat households. Cats with FOCMA antibody titer had a significantly (P less than 0.02) higher prevalence of history of disease than did cats without FOCMA antibody. Diseases included upper respiratory tract infections, abscesses, ear infections, lower urinary tract infections, gastrointestinal disease, pneumonia, uterine infection, lymphadenopathy, fever of unknown origin, and bacterial infections. The FOCMA antibody titer was determined by use of an indirect fluorescent antibody test; titer greater than or equal to 1:16 was considered to be positive results. Lower mean FOCMA antibody titer was observed in young cats with history of disease (P less than 0.05) than in young cats without history of disease or in older cats with or without history of disease. Prevalence of FOCMA antibody titer was identical (38%) in young and adult cats, indicating cats likely were exposed to FeLV as kittens because a higher prevalence of FOCMA antibody titer in older cats would otherwise be expected.
对183只门诊猫以及来自2个封闭的、感染猫白血病病毒（FeLV）的多猫家庭的61只猫的血浆，测定了猫白血病病毒状态以及针对猫肿瘤病毒相关细胞膜抗原（FOCMA）的抗体滴度。具有FOCMA抗体滴度的猫，其疾病史的患病率显著高于（P<0.02）无FOCMA抗体的猫。这些疾病包括上呼吸道感染、脓肿、耳部感染、下尿路感染、胃肠道疾病、肺炎、子宫感染、淋巴结病、不明原因发热以及细菌感染。FOCMA抗体滴度采用间接荧光抗体试验测定；滴度大于或等于1:16被视为阳性结果。有疾病史的幼猫的平均FOCMA抗体滴度低于（P<0.05）无疾病史的幼猫或有或无疾病史的成年猫。幼猫和成年猫中FOCMA抗体滴度的患病率相同（38%），这表明猫很可能在幼猫时期就接触到了FeLV，否则成年猫中FOCMA抗体滴度的患病率会更高。
