Marks H L, Siegel H S, Latimer J W
USDA/ARS-Southeast Poultry Research Laboratory, University of Georgia, Athens 30602.
Poult Sci. 1990 Feb;69(2):205-8. doi: 10.3382/ps.0690205.
Japanese quail (Coturnix coturnix japonica) lines were divergently selected for plasma cholesterol response to adrenocorticotropin (ACTH). Data for Generations 9 to 18 indicated a greater response in the low (L) line than in the high (H) line, which was contrary to selection responses for the first eight generations. During Generations 9 to 18, selection differentials were greater in the H line; however, heritability estimates were greater in the L line. These data suggest caution in the interpretation of early selection responses for plasma cholesterol. Selection for plasma cholesterol response following ACTH injection also resulted in divergence in plasma cholesterol levels in the H and L lines in the absence of ACTH. Body weights at 31 days were greater in the H line than in the L line, suggesting a possible relationship with the plasma cholesterol level.
对日本鹌鹑（日本鹌鹑）品系依据血浆胆固醇对促肾上腺皮质激素（ACTH）的反应进行了 divergent 选择。第9至18代的数据表明，低反应（L）品系的反应比高反应（H）品系更大，这与前八代的选择反应相反。在第9至18代期间，H品系的选择差异更大；然而，L品系的遗传力估计值更大。这些数据表明在解释血浆胆固醇的早期选择反应时需谨慎。在注射ACTH后对血浆胆固醇反应进行选择，也导致了在无ACTH情况下H和L品系血浆胆固醇水平的差异。H品系31日龄时的体重比L品系更大，这表明可能与血浆胆固醇水平存在关联。
