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检测细菌蛋白以了解癌症风险。

Detecting a bacterial protein to understand cancer risk.

机构信息

Department of Medicine, New York University Langone Medical Center, New York, NY 10016, USA.

出版信息

Clin Chem. 2011 Sep;57(9):1331-2. doi: 10.1373/clinchem.2011.165605. Epub 2011 May 17.

DOI:10.1373/clinchem.2011.165605
PMID:21586641
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3938012/
Abstract

Blaser MJ, Perez-Perez GI, Kleanthous H, Cover TL, Peek RM, Chyou PH, et al. Infection with strains possessing is associated with an increased risk of developing adenocarcinoma of the stomach.

摘要

布拉泽尔 MJ、佩雷斯-佩雷斯 GI、克莱恩索斯 H、科弗 TL、皮克 RM、柴友 PH 等人的研究表明，感染具有 的 菌株与胃腺癌发生风险的增加相关。

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本文引用的文献

1
Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer.与细胞毒性和十二指肠溃疡相关的幽门螺杆菌128-kDa免疫显性抗原的分子特征
Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5791-5. doi: 10.1073/pnas.90.12.5791.
2
Cloning and expression of a high-molecular-mass major antigen of Helicobacter pylori: evidence of linkage to cytotoxin production.幽门螺杆菌一种高分子量主要抗原的克隆与表达：与细胞毒素产生相关的证据
Infect Immun. 1993 May;61(5):1799-809. doi: 10.1128/iai.61.5.1799-1809.1993.
3
Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach.感染携带细胞毒素相关基因A（cagA）的幽门螺杆菌菌株会增加患胃腺癌的风险。
Cancer Res. 1995 May 15;55(10):2111-5.
4
Characterization of and human serologic response to proteins in Helicobacter pylori broth culture supernatants with vacuolizing cytotoxin activity.具有空泡毒素活性的幽门螺杆菌肉汤培养上清液中蛋白质的特性及人体血清学反应
Infect Immun. 1990 Mar;58(3):603-10. doi: 10.1128/iai.58.3.603-610.1990.
5
Helicobacter pylori infection and gastric carcinoma among Japanese Americans in Hawaii.夏威夷日裔美国人中的幽门螺杆菌感染与胃癌
N Engl J Med. 1991 Oct 17;325(16):1132-6. doi: 10.1056/NEJM199110173251604.
6
Mucosal IgA recognition of Helicobacter pylori 120 kDa protein, peptic ulceration, and gastric pathology.
Lancet. 1991 Aug 10;338(8763):332-5. doi: 10.1016/0140-6736(91)90477-7.