Department of Pathology, Shrimati Kashibai Navale Medical College and General Hospital, Narhe, Pune-41, India.
Indian J Ophthalmol. 2011 May-Jun;59(3):246-8. doi: 10.4103/0301-4738.81050.
Massive retinal gliosis (MRG) is a rare, benign intraocular condition that results from the proliferation of well-differentiated glial cells. Immunohistochemically, these cells show positivity for glial fibrillary acid protein (GFAP), neuron specific enolase (NSE), and S-100 protein. We encountered a case of a 45-year-old female with loss of vision in the left eye. She had a history of trauma to that eye two years ago. Enucleation was carried out, because malignancy was suspected due to retinal calcification. On the basis of light microscopy and immunohistochemistry (IHC) performed on the enucleated eye, it was diagnosed as massive retinal gliosis.
巨大视网膜神经胶质增生症（MRG）是一种罕见的良性眼内疾病，由分化良好的神经胶质细胞增生引起。免疫组织化学染色显示神经胶质纤维酸性蛋白（GFAP）、神经元特异性烯醇化酶（NSE）和 S-100 蛋白阳性。我们遇到了一位 45 岁女性左眼视力丧失的病例。她两年前左眼曾受过外伤。由于怀疑视网膜钙化是恶性肿瘤，因此进行了眼球摘除术。根据对摘除眼球进行的光镜和免疫组织化学（IHC）检查，诊断为巨大视网膜神经胶质增生症。
