Sharma A, Thapa B, Lavaju P
Department of Ophthalmology, B P Koirala Institute of Health and Sciences, Dharan, Nepal.
Nepal J Ophthalmol. 2011 Jan-Jun;3(1):52-67. doi: 10.3126/nepjoph.v3i1.4280.
Tuberculosis (TB) is an infectious disease responsible for significant morbidity and mortality worldwide. It is a resurgent disease in the developed world. The World Health Organization estimates that one third of the world's population is currently infected, with 9 million new cases occurring annually, leading to 3 million deaths per year (WHO Report, 2007). The disease affects the ocular anterior segment, the posterior segment, and adnexa. The purpose of this review is to describe the ocular manifestations, diagnosis and treatment of tuberculosis and to emphasize the fact that ocular tuberculosis may occur in the absence of systemic clinical activity and may mimic several clinical entities. Various studies have shown a clinical significance of purified protein derivative test results and computerized tomography of the chest while, molecular diagnostic procedures have provided a new approach to establishing the diagnosis of ocular tuberculosis. The current review focuses on the diagnostic modalities, various clinical features, and treatments for management of intraocular tuberculosis recommended in recent publications. It is an update on the manifestations and management of ocular tuberculosis.
结核病是一种在全球范围内导致大量发病和死亡的传染病。在发达国家，它是一种再度流行的疾病。世界卫生组织估计，目前全球三分之一的人口受到感染，每年有900万新发病例，导致每年300万人死亡（《世界卫生组织报告》，2007年）。该疾病可累及眼前段、眼后段及附属器。本综述的目的是描述结核病的眼部表现、诊断和治疗，并强调眼部结核病可能在无全身临床活动的情况下发生，且可能类似多种临床病症这一事实。各种研究表明了结核菌素纯蛋白衍生物试验结果及胸部计算机断层扫描的临床意义，同时，分子诊断程序为眼部结核病的诊断提供了一种新方法。当前综述聚焦于近期出版物中推荐的眼内结核病诊断方法、各种临床特征及治疗方法。它是关于眼部结核病表现及管理的最新内容。
