Moran C A, Kaneko M
Department of Surgical Pathology, Mount Sinai Hospital, New York, New York.
Am J Dermatopathol. 1990 Apr;12(2):182-7.
A case of malignant fibrous histiocytoma of the penis in a 56-year-old Hispanic man is described. The tumor was composed of a proliferation of atypical spindle cells showing the characteristic storiform growth pattern. Immunohistochemical stains were positive for vimentin and alpha-1-antichymotrypsin and negative for keratin, desmin, and S-100 protein antibodies. The unusual location of this tumor in our patient highlights the ubiquitous distribution of this malignant neoplasm. The clinical and histologic differential diagnosis of this lesion is discussed.
本文描述了一名56岁西班牙裔男性阴茎恶性纤维组织细胞瘤的病例。肿瘤由增生的非典型梭形细胞组成,呈现出特征性的席纹状生长模式。免疫组织化学染色显示波形蛋白和α-1抗胰凝乳蛋白酶呈阳性,而角蛋白、结蛋白和S-100蛋白抗体呈阴性。该肿瘤在我们患者身上的不寻常位置凸显了这种恶性肿瘤的广泛分布。本文讨论了该病变的临床和组织学鉴别诊断。