• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

1-[(联苯-4-基)(苯基)甲基]-1H-咪唑(联苯苄唑)

1-[(Biphenyl-4-yl)(phen-yl)meth-yl]-1H-imidazole (bifonazole).

作者信息

Van Eerdenbrugh Bernard, Fanwick Phillip E, Taylor Lynne S

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2010 Sep 30;66(Pt 10):o2649. doi: 10.1107/S1600536810037876.

DOI:10.1107/S1600536810037876
PMID:21587620
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2983152/
Abstract

In the title compound, C(22)H(18)N(2), the dihedral angles formed by the imidazole ring with the phenyl ring and the benzene ring of the biphenyl group are 87.02 (5) and 78.20 (4)°, respectively. In the crystal, mol-ecules inter-act through inter-molecular C-H⋯N hydrogen bonds, forming chains parallel to the b axis. These chains are further linked into a three-dimensional network by C-H⋯π stacking inter-actions.

摘要

在标题化合物C₂₂H₁₈N₂中,咪唑环与联苯基的苯环和苯基形成的二面角分别为87.02 (5)°和78.20 (4)°。在晶体中,分子通过分子间C—H⋯N氢键相互作用,形成平行于b轴的链。这些链通过C—H⋯π堆积相互作用进一步连接成三维网络。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a749/2983152/c7296038d399/e-66-o2649-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a749/2983152/c7296038d399/e-66-o2649-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a749/2983152/c7296038d399/e-66-o2649-fig1.jpg

相似文献

1
1-[(Biphenyl-4-yl)(phen-yl)meth-yl]-1H-imidazole (bifonazole).1-[(联苯-4-基)(苯基)甲基]-1H-咪唑(联苯苄唑)
Acta Crystallogr Sect E Struct Rep Online. 2010 Sep 30;66(Pt 10):o2649. doi: 10.1107/S1600536810037876.
2
2-[2-(4-Meth-oxy-phen-yl)-4,5-diphenyl-1H-imidazol-1-yl]ethanol.2-[2-(4-甲氧基苯基)-4,5-二苯基-1H-咪唑-1-基]乙醇
Acta Crystallogr Sect E Struct Rep Online. 2013 Mar 2;69(Pt 4):o474-5. doi: 10.1107/S1600536813004285. Print 2013 Apr 1.
3
2-(3,4-Di-meth-oxy-phen-yl)-1-pentyl-4,5-diphenyl-1H-imidazole.2-(3,4-二甲氧基苯基)-1-戊基-4,5-二苯基-1H-咪唑
Acta Crystallogr Sect E Struct Rep Online. 2013 Nov 27;69(Pt 12):o1833-4. doi: 10.1107/S1600536813031759.
4
2-[2-(2-Nitro-phen-yl)-4,5-diphenyl-1H-imidazol-1-yl]-3-phenyl-propan-1-ol.2-[2-(2-硝基苯基)-4,5-二苯基-1H-咪唑-1-基]-3-苯基丙-1-醇
Acta Crystallogr Sect E Struct Rep Online. 2014 Apr 30;70(Pt 5):o621. doi: 10.1107/S1600536814008770. eCollection 2014 May 1.
5
Crystal structures of three carbazole derivatives: 12-ethyl-7-phenyl-sulfonyl-7-benzofuro[2,3-]carbazole, (1), 2-(4,5-dimeth-oxy-2-nitro-phen-yl)-4-hy-droxy-9-phenyl-sulfonyl-9-carbazole-3-carbaldehyde, (2), and 12-phenyl-7-phenyl-sulfonyl-7-benzofuro[2,3-]carbazole, (3).三种咔唑衍生物的晶体结构:12-乙基-7-苯基磺酰基-7-苯并呋喃并[2,3-]咔唑,(1);2-(4,5-二甲氧基-2-硝基苯基)-4-羟基-9-苯基磺酰基-9-咔唑-3-甲醛,(2);以及12-苯基-7-苯基磺酰基-7-苯并呋喃并[2,3-]咔唑,(3)。
Acta Crystallogr E Crystallogr Commun. 2016 Nov 4;72(Pt 12):1744-1750. doi: 10.1107/S2056989016016819. eCollection 2016 Dec 1.
6
N-[2-({[1-(4-Chloro-phen-yl)-1H-pyrazol-3-yl]-oxy}meth-yl)phen-yl]-N-meth-oxy-hydrazinecarboxamide.N-[2-({[1-(4-氯苯基)-1H-吡唑-3-基]氧基}甲基)苯基]-N-甲氧基肼甲酰胺
Acta Crystallogr Sect E Struct Rep Online. 2012 Oct 1;68(Pt 10):o2916. doi: 10.1107/S1600536812038214. Epub 2012 Sep 12.
7
4-[(4-Chloro-phen-yl)(5-hydr-oxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)meth-yl]-5-methyl-2-phenyl-1H-pyrazol-3(2H)-one.4-[(4-氯苯基)(5-羟基-3-甲基-1-苯基-1H-吡唑-4-基)甲基]-5-甲基-2-苯基-1H-吡唑-3(2H)-酮
Acta Crystallogr Sect E Struct Rep Online. 2008 Nov 8;64(Pt 12):o2301-2. doi: 10.1107/S1600536808036088.
8
2-(4-Meth-oxy-phen-yl)-4,5-diphenyl-1-(prop-2-en-1-yl)-1H-imidazole.2-(4-甲氧基苯基)-4,5-二苯基-1-(2-丙烯-1-基)-1H-咪唑
Acta Crystallogr Sect E Struct Rep Online. 2012 Nov 1;68(Pt 11):o3113-4. doi: 10.1107/S1600536812041979. Epub 2012 Oct 13.
9
Ethyl 1-phenyl-2-[4-(trifluoro-meth-oxy)phen-yl]-1H-benzimidazole-5-carboxyl-ate.1-苯基-2-[4-(三氟甲氧基)苯基]-1H-苯并咪唑-5-羧酸乙酯
Acta Crystallogr Sect E Struct Rep Online. 2012 Sep 1;68(Pt 9):o2715-6. doi: 10.1107/S1600536812034903. Epub 2012 Aug 15.
10
1-{(E)-[3-(1H-Imidazol-1-yl)-1-phenyl-propyl-idene]amino}-3-(2-methyl-phen-yl)urea.1-{(E)-[3-(1H-咪唑-1-基)-1-苯基-亚丙基]氨基}-3-(2-甲基-苯基)脲
Acta Crystallogr Sect E Struct Rep Online. 2012 Jun 1;68(Pt 6):o1848-9. doi: 10.1107/S1600536812022659. Epub 2012 May 23.

引用本文的文献

1
Structural and Spectroscopic Properties of Isoconazole and Bifonazole-Experimental and Theoretical Studies.异康唑和比佛拉唑的结构和光谱性质。实验和理论研究。
Int J Mol Sci. 2022 Dec 28;24(1):520. doi: 10.3390/ijms24010520.

本文引用的文献

1
Structure validation in chemical crystallography.化学晶体学中的结构验证
Acta Crystallogr D Biol Crystallogr. 2009 Feb;65(Pt 2):148-55. doi: 10.1107/S090744490804362X. Epub 2009 Jan 20.
2
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
3
Bifonazole. A review of its antimicrobial activity and therapeutic use in superficial mycoses.联苯苄唑。其抗微生物活性及在浅表真菌病治疗应用的综述。
Drugs. 1989 Aug;38(2):204-25. doi: 10.2165/00003495-198938020-00004.