• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

（E）-4-羟基-2-[(2-羟基苯基)亚氨基甲基]苯酚盐

(E)-4-Hy-droxy-2-[(2-hy-droxy-phen-yl)iminiometh-yl]phenolate.

作者信息

Eltayeb Naser Eltaher, Teoh Siang Guan, Fun Hoong-Kun, Chantrapromma Suchada

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 5;66(Pt 7):o1536-7. doi: 10.1107/S1600536810020295.

DOI:10.1107/S1600536810020295
PMID:21587785
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3006709/
Abstract

The title compound, C(13)H(11)NO(3), crystallizes in a zwitterionic form and has a trans configuration about the C=N bond. The mol-ecule is almost planar, the dihedral angle between the two benzene rings being 4.32 (8)°. The two hy-droxy substit-uents are coplanar with each of their attached benzene rings [r.m.s. deviations of 0.0053 (2) and 0.0052 (2) Å]. An intra-molecular N-H⋯O hydrogen bond formed between the iminium N and the phenolate O atom generates an S(6) ring motif. In the crystal, the mol-ecules are linked through O-H⋯O hydrogen bonds into chains along [110]. Two neighbouring chains are further connected through O-H⋯O hydrogen bonds in an anti-parallel manner. π-π inter-actions are also observed, with centroid-centroid distances of 3.7115 (19) and 3.743 (2) Å.

摘要

标题化合物C(13)H(11)NO(3)以两性离子形式结晶，且C=N键具有反式构型。分子几乎呈平面状，两个苯环之间的二面角为4.32 (8)°。两个羟基取代基与其相连的每个苯环共面[r.m.s.偏差分别为0.0053 (2)和0.0052 (2) Å]。亚胺鎓N与酚盐O原子之间形成的分子内N-H⋯O氢键生成了一个S(6)环结构单元。在晶体中，分子通过O-H⋯O氢键沿[110]方向连接成链。两条相邻的链通过O-H⋯O氢键以反平行方式进一步连接。还观察到π-π相互作用，质心间距为3.7115 (19)和3.743 (2) Å。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2766/3006709/497a7828533c/e-66-o1536-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2766/3006709/4b4834b0bd6f/e-66-o1536-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2766/3006709/497a7828533c/e-66-o1536-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2766/3006709/4b4834b0bd6f/e-66-o1536-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2766/3006709/497a7828533c/e-66-o1536-fig2.jpg

相似文献

1
(E)-4-Hy-droxy-2-[(2-hy-droxy-phen-yl)iminiometh-yl]phenolate.（E）-4-羟基-2-[(2-羟基苯基)亚氨基甲基]苯酚盐
Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 5;66(Pt 7):o1536-7. doi: 10.1107/S1600536810020295.
2
2-[(E)-(3-Carb-oxy-4-hy-droxy-phen-yl)iminiometh-yl]-4-chloro-phenolate.2-[(E)-(3-羧基-4-羟基苯基)亚氨基甲基]-4-氯酚盐
Acta Crystallogr Sect E Struct Rep Online. 2010 Aug 28;66(Pt 9):o2466. doi: 10.1107/S1600536810033362.
3
(E)-4-Allyl-2-[(2-hydroxy-phen-yl)iminiometh-yl]-6-methoxy-phenolate.（E）-4-烯丙基-2-[(2-羟基苯基)亚氨基甲基]-6-甲氧基苯酚盐
Acta Crystallogr Sect E Struct Rep Online. 2010 Mar 27;66(Pt 4):o934-5. doi: 10.1107/S160053681000838X.
4
(E)-2-[(2-Ethyl-phen-yl)iminiometh-yl]-6-hydroxy-phenolate.（E）-2- [（2-乙基-苯基）亚氨基甲基] -6-羟基苯酚盐
Acta Crystallogr Sect E Struct Rep Online. 2010 Jan 27;66(Pt 2):o449. doi: 10.1107/S1600536810002503.
5
(E)-4-Bromo-2-[(2-hydroxy-phen-yl)iminiometh-yl]phenolate.（E）-4-溴-2-[(2-羟基苯基)亚氨基甲基]苯酚盐
Acta Crystallogr Sect E Struct Rep Online. 2010 May 8;66(Pt 6):o1262-3. doi: 10.1107/S1600536810015230.
6
5-Hy-droxy-2-{(E)-[(3-nitro-phen-yl)iminio]meth-yl}phenolate.5-羟基-2-{（E）-[（3-硝基苯基）亚氨基]甲基}苯酚盐
Acta Crystallogr Sect E Struct Rep Online. 2012 Sep 1;68(Pt 9):o2622. doi: 10.1107/S1600536812033740. Epub 2012 Aug 1.
7
N'-[(E)-1-(2-Hy-droxy-phen-yl)ethyl-idene]pyrazine-2-carbohydrazide.N'-[(E)-1-(2-羟基苯基)亚乙基]吡嗪-2-碳酰肼
Acta Crystallogr Sect E Struct Rep Online. 2013 Aug 14;69(Pt 9):o1419. doi: 10.1107/S1600536813022137. eCollection 2013.
8
2-[(E)-({4-[(4,6-Dimethyl-pyrimidin-2-yl)sulfamo-yl]phen-yl}iminio)meth-yl]-6-hy-droxy-phenolate.2-[(E)-({4-[(4,6-二甲基嘧啶-2-基)氨磺酰基]苯基}亚氨基)甲基]-6-羟基苯酚盐
Acta Crystallogr Sect E Struct Rep Online. 2012 Sep 1;68(Pt 9):o2687. doi: 10.1107/S1600536812034757. Epub 2012 Aug 11.
9
(E)-1-(2,4-Di-nitro-phen-yl)-2-(3-eth-oxy-4-hy-droxy-benzyl-idene)hydrazine.（E）-1-（2,4-二硝基苯基）-2-（3-乙氧基-4-羟基亚苄基）肼
Acta Crystallogr Sect E Struct Rep Online. 2013 Dec 24;70(Pt 1):o89-90. doi: 10.1107/S1600536813033989. eCollection 2014 Jan 1.
10
Crystal structures of (E)-N'-(2-hy-droxy-5-methyl-benzyl-idene)isonicotinohydrazide and (E)-N'-(5-fluoro-2-hy-droxy-benzyl-idene)isonicotinohydrazide.（E）-N'-（2-羟基-5-甲基亚苄基）异烟肼和（E）-N'-（5-氟-2-羟基亚苄基）异烟肼的晶体结构
Acta Crystallogr E Crystallogr Commun. 2016 Jun 17;72(Pt 7):980-3. doi: 10.1107/S2056989016009762. eCollection 2016 Jul 1.

引用本文的文献

1
Crystal structure and Hirshfeld surface analysis of ()-6-[(2-hy-droxy-4-methyl-anilino)-methyl-idene]-4-methyl-cyclo-hexa-2,4-dien-1-one.（）-6-[(2-羟基-4-甲基苯胺基)-亚甲基]-4-甲基环己-2,4-二烯-1-酮的晶体结构与 Hirshfeld 表面分析
Acta Crystallogr E Crystallogr Commun. 2019 May 14;75(Pt 6):785-788. doi: 10.1107/S2056989019006583. eCollection 2019 Jun 1.
2
Crystal structure of 2-{(E)-[(2-hy-droxy-phen-yl)iminium-yl]meth-yl}-4-methyl-phenolate.2-{(E)-[(2-羟基苯基)亚氨基甲基]甲基}-4-甲基苯酚盐的晶体结构
Acta Crystallogr E Crystallogr Commun. 2015 Apr 9;71(Pt 5):o288. doi: 10.1107/S2056989015006374. eCollection 2015 May 1.
3

本文引用的文献

1
(E)-2-[(2-Hydroxy-ethyl)iminiometh-yl]-6-methoxy-phenolate.
Acta Crystallogr Sect E Struct Rep Online. 2009 Feb 21;65(Pt 3):o559. doi: 10.1107/S1600536809005297.
2
(E)-4-Allyl-2-[(2-hydroxy-phen-yl)iminiometh-yl]-6-methoxy-phenolate.（E）-4-烯丙基-2-[(2-羟基苯基)亚氨基甲基]-6-甲氧基苯酚盐
Acta Crystallogr Sect E Struct Rep Online. 2010 Mar 27;66(Pt 4):o934-5. doi: 10.1107/S160053681000838X.
3
(E)-4-Bromo-2-[(2-hydroxy-phen-yl)iminiometh-yl]phenolate.（E）-4-溴-2-[(2-羟基苯基)亚氨基甲基]苯酚盐
(E)-2-{[1-Carb-oxy-2-(1H-indol-3-yl)ethyl-iminio]meth-yl}-6-hy-droxy-phenolate.
（E）-2-{[1-羧基-2-（1H-吲哚-3-基）乙基亚氨基]甲基}-6-羟基苯酚盐
Acta Crystallogr Sect E Struct Rep Online. 2011 Sep 1;67(Pt 9):o2389. doi: 10.1107/S1600536811031709. Epub 2011 Aug 27.
Acta Crystallogr Sect E Struct Rep Online. 2010 May 8;66(Pt 6):o1262-3. doi: 10.1107/S1600536810015230.
4
2-((E)-{2-[(E)-2,3-Dihydroxy-benzyl-ideneamino]-5-methyl-phen-yl}iminiometh-yl)-6-hydroxy-phenolate.2-((E)-{2-[(E)-2,3-二羟基-苄叉氨基]-5-甲基-苯基}亚氨基甲基)-6-羟基苯酚盐
Acta Crystallogr Sect E Struct Rep Online. 2009 Aug 8;65(Pt 9):o2065-6. doi: 10.1107/S1600536809029833.
5
Structure validation in chemical crystallography.化学晶体学中的结构验证
Acta Crystallogr D Biol Crystallogr. 2009 Feb;65(Pt 2):148-55. doi: 10.1107/S090744490804362X. Epub 2009 Jan 20.
6
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
7
Synthesis and biological activity of Schiff and Mannich bases bearing 2,4-dichloro-5-fluorophenyl moiety.含2,4-二氯-5-氟苯基部分的席夫碱和曼尼希碱的合成及生物活性
Bioorg Med Chem. 2006 Nov 15;14(22):7482-9. doi: 10.1016/j.bmc.2006.07.015. Epub 2006 Aug 1.
8
Abacavir prodrugs: microwave-assisted synthesis and their evaluation of anti-HIV activities.阿巴卡韦前药：微波辅助合成及其抗HIV活性评估
Bioorg Med Chem Lett. 2006 Apr 15;16(8):2127-9. doi: 10.1016/j.bmcl.2006.01.050. Epub 2006 Feb 3.
9
Synthesis and cytotoxicity of gossypol related compounds.棉酚相关化合物的合成及其细胞毒性
Eur J Med Chem. 2000 Sep;35(9):805-13. doi: 10.1016/s0223-5234(00)00165-3.