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非酶体系中黄酮类化合物的超氧化物清除特性

Superoxide scavenging properties of flavonoids in a non-enzymic system.

作者信息

Huguet A I, Máñez S, Alcaraz M J

机构信息

Departament de Farmacologia i Farmacotècnia, Facultat de Farmacia, Valencia, Spain.

出版信息

Z Naturforsch C J Biosci. 1990 Jan-Feb;45(1-2):19-24. doi: 10.1515/znc-1990-1-205.

DOI:10.1515/znc-1990-1-205
PMID:2158783
Abstract

The superoxide anion scavenging activity of 38 flavonoids, some of them isolated from Sideritis mugronensis, Sideritis javalambrensis and Cayaponia tayuya were investigated by measurement of their inhibition of nitroblue tetrazolium reduction. Isoorientin, orientin, amentoflavone, leucocyanidol, eriodictyol, datiscetin and robinetin behaved as potent scavengers and structure-activity relationships were established.

摘要

通过测定38种黄酮类化合物对氮蓝四唑还原的抑制作用,研究了其中一些从穆格罗铁角蕨、哈瓦拉姆布铁角蕨和塔尤亚卡亚波尼亚中分离得到的黄酮类化合物的超氧阴离子清除活性。异荭草素、荭草素、穗花杉双黄酮、无色花青素、圣草酚、黄杞苷和刺槐素表现出较强的清除能力,并建立了构效关系。

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Superoxide scavenging properties of flavonoids in a non-enzymic system.非酶体系中黄酮类化合物的超氧化物清除特性
Z Naturforsch C J Biosci. 1990 Jan-Feb;45(1-2):19-24. doi: 10.1515/znc-1990-1-205.
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Antioxidant activity of flavonoids from Sideritis javalambrensis.来自贾瓦拉姆布勒山铁角蕨的黄酮类化合物的抗氧化活性。
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Flavonoids as superoxide scavengers and antioxidants.黄酮类化合物作为超氧化物清除剂和抗氧化剂。
Free Radic Biol Med. 1990;9(1):19-21. doi: 10.1016/0891-5849(90)90045-k.
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[Superoxide-scavenging activity of carnosine in the presence of copper and zinc ions].[肌肽在铜离子和锌离子存在下的超氧化物清除活性]
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Inhibition of nitroblue tetrazolium reduction by cuprein (superoxide dismutase), Cu(tyr)2 and Cu(lys)2.铜蛋白(超氧化物歧化酶)、Cu(tyr)2和Cu(lys)2对氮蓝四唑还原的抑制作用。
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Superoxide generated by pyrogallol reduces highly water-soluble tetrazolium salt to produce a soluble formazan: a simple assay for measuring superoxide anion radical scavenging activities of biological and abiological samples.焦性没食子酸产生的超氧阴离子将水溶性四唑盐还原生成可溶性甲臜:一种用于测量生物和非生物样品中超氧阴离子自由基清除活性的简单测定法。
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[Changes in superoxide dismutase activity in the presence of electron donors and acceptors].
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Nitroblue tetrazolium reduction in lymphocytes.淋巴细胞中的硝基蓝四氮唑还原反应。
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The application of ultrasounds for detection of scavenging of superoxide anions by drugs.超声在检测药物清除超氧阴离子中的应用。
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