非酶体系中黄酮类化合物的超氧化物清除特性
Superoxide scavenging properties of flavonoids in a non-enzymic system.
作者信息
Huguet A I, Máñez S, Alcaraz M J
机构信息
Departament de Farmacologia i Farmacotècnia, Facultat de Farmacia, Valencia, Spain.
出版信息
Z Naturforsch C J Biosci. 1990 Jan-Feb;45(1-2):19-24. doi: 10.1515/znc-1990-1-205.
PMID:2158783
Abstract
The superoxide anion scavenging activity of 38 flavonoids, some of them isolated from Sideritis mugronensis, Sideritis javalambrensis and Cayaponia tayuya were investigated by measurement of their inhibition of nitroblue tetrazolium reduction. Isoorientin, orientin, amentoflavone, leucocyanidol, eriodictyol, datiscetin and robinetin behaved as potent scavengers and structure-activity relationships were established.
摘要
通过测定38种黄酮类化合物对氮蓝四唑还原的抑制作用，研究了其中一些从穆格罗铁角蕨、哈瓦拉姆布铁角蕨和塔尤亚卡亚波尼亚中分离得到的黄酮类化合物的超氧阴离子清除活性。异荭草素、荭草素、穗花杉双黄酮、无色花青素、圣草酚、黄杞苷和刺槐素表现出较强的清除能力，并建立了构效关系。
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