• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

2-氨基-5-[(E)-(呋喃-2-基亚甲基)氨基]噻吩-3,4-二羧酸二乙酯

Diethyl 2-amino-5-[(E)-(furan-2-yl-methyl-idene)amino]-thio-phene-3,4-di-carboxyl-ate.

作者信息

Dufresne Stéphane, Skene W G

机构信息

Department of Chemistry, University of Montreal, CP 6128, succ. Centre-ville, Montréal, Québec, Canada H3C 3J7.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2010 Oct 31;66(Pt 11):o3027. doi: 10.1107/S1600536810043746.

DOI:10.1107/S1600536810043746
PMID:21589183
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3009046/
Abstract

In the crystal structure of the title compound, C(15)H(16)N(2)O(5)S, the azomethine adopts the E configuration. The two heterocyclic rings adopt an anti-periplanar orientation. The mean planes of the thio-phene and furan rings are twisted by 2.51 (4)°. The crystal structure exhibits inter-molecular N-H⋯O hydrogen bonding. π-π stacking is also observed, the centroid-to-centroid distance being 3.770 (4) Å.

摘要

在标题化合物C(15)H(16)N(2)O(5)S的晶体结构中，亚甲胺采取E构型。两个杂环采取反式共平面取向。噻吩环和呋喃环的平均平面扭转了2.51 (4)°。晶体结构呈现分子间N-H⋯O氢键。还观察到π-π堆积，质心到质心距离为3.770 (4) Å。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d92b/3009046/64eced166c6c/e-66-o3027-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d92b/3009046/0ea0731e0cdf/e-66-o3027-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d92b/3009046/2de2d8aa5b67/e-66-o3027-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d92b/3009046/64eced166c6c/e-66-o3027-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d92b/3009046/0ea0731e0cdf/e-66-o3027-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d92b/3009046/2de2d8aa5b67/e-66-o3027-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d92b/3009046/64eced166c6c/e-66-o3027-fig3.jpg

相似文献

1
Diethyl 2-amino-5-[(E)-(furan-2-yl-methyl-idene)amino]-thio-phene-3,4-di-carboxyl-ate.2-氨基-5-[(E)-(呋喃-2-基亚甲基)氨基]噻吩-3,4-二羧酸二乙酯
Acta Crystallogr Sect E Struct Rep Online. 2010 Oct 31;66(Pt 11):o3027. doi: 10.1107/S1600536810043746.
2
Diethyl 2,5-bis-[(2,3-dihydro-thieno[3,4-b][1,4]dioxin-5-yl)methyl-idene-amino]-thio-phene-3,4-dicarboxyl-ate acetone monosolvate.2,5-双-[(2,3-二氢-噻吩并[3,4-b][1,4]二氧杂环己烯-5-基)亚甲基氨基]-噻吩-3,4-二羧酸二乙酯丙酮单溶剂合物
Acta Crystallogr Sect E Struct Rep Online. 2011 Dec 1;67(Pt 12):o3138. doi: 10.1107/S160053681104339X. Epub 2011 Nov 2.
3
Crystal structures of three 1-oxo-1,2-di-hydro-naphthalene derivatives: dimethyl 4-(4-meth-oxy-phen-yl)-2-(4-methyl-phen-yl)-1-oxo-1,2-di-hydro-naphthalene-2,3-di-carboxyl-ate, dimethyl 1-oxo-2-(pyren-4-yl)-4-(thio-phen-2-yl)-1,2-di-hydro-naphthalene-2,3-di-carboxyl-ate and ethyl 1-oxo-2-phenyl-2,4-bis-(thio-phen-2-yl)-1,2-di-hydro-naphthalene-3-carboxyl-ate.三种1-氧代-1,2-二氢萘衍生物的晶体结构：4-(4-甲氧基苯基)-2-(4-甲基苯基)-1-氧代-1,2-二氢萘-2,3-二羧酸二甲酯、1-氧代-2-(芘-4-基)-4-(噻吩-2-基)-1,2-二氢萘-2,3-二羧酸二甲酯和1-氧代-2-苯基-2,4-双(噻吩-2-基)-1,2-二氢萘-3-羧酸乙酯。
Acta Crystallogr E Crystallogr Commun. 2017 Jan 13;73(Pt 2):177-182. doi: 10.1107/S2056989017000469. eCollection 2017 Feb 1.
4
Diethyl 2,5-bis-[(1E)-(1H-pyrrol-2-yl-methyl-idene)amino]-thio-phene-3,4-dicarboxyl-ate.2,5-双-[(1E)-(1H-吡咯-2-基亚甲基)氨基]噻吩-3,4-二羧酸二乙酯
Acta Crystallogr Sect E Struct Rep Online. 2011 Sep 1;67(Pt 9):o2302. doi: 10.1107/S1600536811031576. Epub 2011 Aug 11.
5
Diethyl 2-amino-5-[(E)-(1-methyl-1H-pyrrol-2-yl)methylideneamino]thiophene-3,4-dicarboxylate.2-氨基-5-[(E)-(1-甲基-1H-吡咯-2-基)亚甲基氨基]噻吩-3,4-二羧酸二乙酯
Acta Crystallogr Sect E Struct Rep Online. 2010 Nov 20;66(Pt 12):o3221. doi: 10.1107/S1600536810046775.
6
Crystal structure of 2-{[(5-nitro-thio-phen-2-yl)methyl-idene]amino}-phenol.2-{[(5-硝基-噻吩-2-基)亚甲基]氨基}-苯酚的晶体结构
Acta Crystallogr E Crystallogr Commun. 2015 May 23;71(Pt 6):o418. doi: 10.1107/S2056989015009202. eCollection 2015 Jun 1.
7
Crystal structure of ethyl 5-acetyl-2-{[(di-methyl-amino)-methyl-idene]amino}-4-methyl-thio-phene-3-carboxyl-ate.5-乙酰基-2-{[(二甲基氨基)亚甲基]氨基}-4-甲基硫代噻吩-3-羧酸乙酯的晶体结构
Acta Crystallogr E Crystallogr Commun. 2015 Sep 17;71(Pt 10):o762-3. doi: 10.1107/S2056989015016217. eCollection 2015 Oct 1.
8
Diethyl 2-[(1-methyl-1H-pyrrol-2-yl)methyl-ene-amino]-5-(2-thienylmethyl-ene-amino)thio-phene-3,4-dicarboxyl-ate.2-[(1-甲基-1H-吡咯-2-基)亚甲基氨基]-5-(2-噻吩基亚甲基氨基)噻吩-3,4-二甲酸二乙酯
Acta Crystallogr Sect E Struct Rep Online. 2008 Apr 2;64(Pt 5):o782. doi: 10.1107/S160053680800799X.
9
Crystal structure of diethyl 2-amino-5-{4-[bis-(4-methyl-phen-yl)amino]-benzamido}-thio-phene-3,4-di-carboxyl-ate.
Acta Crystallogr E Crystallogr Commun. 2019 Apr 9;75(Pt 5):589-592. doi: 10.1107/S2056989019003864. eCollection 2019 May 1.
10
Crystal structure of ethyl (2S,2'R)-1'-benzyl-3-oxo-3H-di-spiro-[1-benzo-thio-phene-2,3'-pyrrolidine-2',11''-indeno[1,2-b]quinoxaline]-4'-carboxyl-ate.（2S，2'R）-1'-苄基-3-氧代-3H-二螺-[1-苯并噻吩-2，3'-吡咯烷-2'，11''-茚并[1,2-b]喹喔啉]-4'-羧酸乙酯的晶体结构
Acta Crystallogr E Crystallogr Commun. 2015 Feb 21;71(Pt 3):o195-6. doi: 10.1107/S2056989015003187. eCollection 2015 Mar 1.

引用本文的文献

1
Crystal structure of diethyl 2-amino-5-{4-[bis-(4-methyl-phen-yl)amino]-benzamido}-thio-phene-3,4-di-carboxyl-ate.
Acta Crystallogr E Crystallogr Commun. 2019 Apr 9;75(Pt 5):589-592. doi: 10.1107/S2056989019003864. eCollection 2019 May 1.
2
(4-Methyl-phen-yl)[2-(thio-phen-2-ylcarbon-yl)phen-yl]methanone.（4-甲基-苯基）[2-（噻吩-2-基羰基）苯基]甲酮
Acta Crystallogr Sect E Struct Rep Online. 2011 Sep 1;67(Pt 9):o2349. doi: 10.1107/S1600536811032478. Epub 2011 Aug 17.
3
Diethyl 2,5-bis-[(1E)-(1H-pyrrol-2-yl-methyl-idene)amino]-thio-phene-3,4-dicarboxyl-ate.2,5-双-[(1E)-(1H-吡咯-2-基亚甲基)氨基]噻吩-3,4-二羧酸二乙酯

本文引用的文献

1
Unsymmetric pyrrole, thiophene, and furan-conjugated comonomers prepared using azomethine connections: potential new monomers for alternating homocoupled products.使用甲亚胺连接制备的不对称吡咯、噻吩和呋喃共轭共聚单体：交替均偶联产物的潜在新型单体。
J Org Chem. 2008 May 16;73(10):3859-66. doi: 10.1021/jo8002503. Epub 2008 Apr 15.
2
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
Acta Crystallogr Sect E Struct Rep Online. 2011 Sep 1;67(Pt 9):o2302. doi: 10.1107/S1600536811031576. Epub 2011 Aug 11.
4
Diethyl 2-{[3-(2-meth-oxy-benz-yl)thio-phen-2-yl]methyl-idene}malonate.2-{[3-(2-甲氧基苄基)硫代苯-2-基]亚甲基}丙二酸二乙酯
Acta Crystallogr Sect E Struct Rep Online. 2011 Jul 1;67(Pt 7):o1688. doi: 10.1107/S1600536811022525. Epub 2011 Jun 18.
5
Diethyl 2-amino-5-[(E)-(1-methyl-1H-pyrrol-2-yl)methylideneamino]thiophene-3,4-dicarboxylate.2-氨基-5-[(E)-(1-甲基-1H-吡咯-2-基)亚甲基氨基]噻吩-3,4-二羧酸二乙酯
Acta Crystallogr Sect E Struct Rep Online. 2010 Nov 20;66(Pt 12):o3221. doi: 10.1107/S1600536810046775.