• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

(2R,3S)-2-羟基-3-(4-甲基苯磺酰胺基)-3-苯基丙酸甲酯

(2R,3S)-Methyl 2-hy-droxy-3-(4-methyl-benzene-sulfonamido)-3-phenyl-propano-ate.

作者信息

Fadlalla Mohamed I, Friedrich Holger B, Maguire Glenn E M, Omondi Bernard

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2010 Nov 24;66(Pt 12):o3279-80. doi: 10.1107/S160053681004780X.

DOI:10.1107/S160053681004780X
PMID:21589560
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3011734/
Abstract

In the title mol-ecule, C(17)H(19)NO(5)S, the p-tolyl ring is oriented approximately parallel to the phenyl ring [dihedral angle = 17.2 (1)°], resulting in an intra-molecular π-π inter-ation [centroid-centroid distance = 3.184 (10) Å]. In the crystal, mol-ecules are linked through O-H⋯O and C-H⋯O hydrogen bonds, forming hydrogen-bonded sheets lying diagonally across the ac face.

摘要

在标题分子C(17)H(19)NO(5)S中，对甲苯基环与苯环近似平行排列[二面角 = 17.2 (1)°]，从而产生分子内π-π相互作用[质心间距 = 3.184 (10) Å]。在晶体中，分子通过O—H⋯O和C—H⋯O氢键相连，形成沿ac面斜对角排列的氢键层。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b86/3011734/b55a5cc7a4e8/e-66-o3279-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b86/3011734/bf5bb103817f/e-66-o3279-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b86/3011734/616223be2473/e-66-o3279-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b86/3011734/b55a5cc7a4e8/e-66-o3279-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b86/3011734/bf5bb103817f/e-66-o3279-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b86/3011734/616223be2473/e-66-o3279-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2b86/3011734/b55a5cc7a4e8/e-66-o3279-fig3.jpg

相似文献

1
(2R,3S)-Methyl 2-hy-droxy-3-(4-methyl-benzene-sulfonamido)-3-phenyl-propano-ate.(2R,3S)-2-羟基-3-(4-甲基苯磺酰胺基)-3-苯基丙酸甲酯
Acta Crystallogr Sect E Struct Rep Online. 2010 Nov 24;66(Pt 12):o3279-80. doi: 10.1107/S160053681004780X.
2
Ethyl 1-(2-hy-droxy-eth-yl)-2-p-tolyl-1H-benzimidazole-5-carboxyl-ate.1-(2-羟乙基)-2-对甲苯基-1H-苯并咪唑-5-羧酸乙酯
Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 5;66(Pt 7):o1590-1. doi: 10.1107/S1600536810020799.
3
Crystal structure of (5-chloro-2-hy-droxy-phen-yl)(3-methyl-isoxazolo[5,4-b]pyridin-5-yl)methanone.（5-氯-2-羟基苯基）（3-甲基异恶唑并[5,4-b]吡啶-5-基）甲酮的晶体结构
Acta Crystallogr E Crystallogr Commun. 2015 Oct 24;71(Pt 11):o875-6. doi: 10.1107/S2056989015019635. eCollection 2015 Nov 1.
4
Ethyl 1-(2-hy-droxy-eth-yl)-2-phenyl-1H-benzimidazole-5-carboxyl-ate.1-(2-羟乙基)-2-苯基-1H-苯并咪唑-5-羧酸乙酯
Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 26;66(Pt 7):o1824-5. doi: 10.1107/S1600536810023639.
5
Ethyl 2-[2-(4-hy-droxy-3-meth-oxy-benzyl-idene)hydrazin-1-yl-idene]-3,4-dimethyl-2,3-dihydro-1,3-thia-zole-5-carboxyl-ate.2-[2-(4-羟基-3-甲氧基苄叉基)肼-1-亚基]-3,4-二甲基-2,3-二氢-1,3-噻唑-5-羧酸乙酯
Acta Crystallogr Sect E Struct Rep Online. 2012 Nov 1;68(Pt 11):o3213-4. doi: 10.1107/S1600536812043772. Epub 2012 Oct 27.
6
2-Hy-droxy-5-[(E)-(1H-indol-3-yl-methyl-idene)aza-nium-yl]benzoate.2-羟基-5-[(E)-(1H-吲哚-3-基亚甲基)氮鎓基]苯甲酸酯
Acta Crystallogr Sect E Struct Rep Online. 2010 Nov 27;66(Pt 12):o3314. doi: 10.1107/S1600536810048579.
7
Methyl 2-[(tert-but-oxy-carbon-yl)amino]-3-(4-hy-droxy-phen-yl)propano-ate.2-[(叔丁氧基羰基)氨基]-3-(4-羟基苯基)丙酸甲酯
Acta Crystallogr Sect E Struct Rep Online. 2013 Aug 3;69(Pt 9):o1372. doi: 10.1107/S160053681301979X. eCollection 2013.
8
(E)-4-Hy-droxy-2-[(2-hy-droxy-phen-yl)iminiometh-yl]phenolate.（E）-4-羟基-2-[(2-羟基苯基)亚氨基甲基]苯酚盐
Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 5;66(Pt 7):o1536-7. doi: 10.1107/S1600536810020295.
9
N'-(3-Eth-oxy-2-hy-droxy-benzyl-idene)-2-hy-droxy-3-methyl-benzohydrazide.N'-(3-乙氧基-2-羟基苯亚甲基)-2-羟基-3-甲基苯甲酰肼
Acta Crystallogr Sect E Struct Rep Online. 2012 Feb 1;68(Pt 2):o500. doi: 10.1107/S1600536812002127. Epub 2012 Jan 21.
10
Crystal structures of three carbazole derivatives: 12-ethyl-7-phenyl-sulfonyl-7-benzofuro[2,3-]carbazole, (1), 2-(4,5-dimeth-oxy-2-nitro-phen-yl)-4-hy-droxy-9-phenyl-sulfonyl-9-carbazole-3-carbaldehyde, (2), and 12-phenyl-7-phenyl-sulfonyl-7-benzofuro[2,3-]carbazole, (3).三种咔唑衍生物的晶体结构：12-乙基-7-苯基磺酰基-7-苯并呋喃并[2,3-]咔唑，（1）；2-（4,5-二甲氧基-2-硝基苯基）-4-羟基-9-苯基磺酰基-9-咔唑-3-甲醛，（2）；以及12-苯基-7-苯基磺酰基-7-苯并呋喃并[2,3-]咔唑，（3）。
Acta Crystallogr E Crystallogr Commun. 2016 Nov 4;72(Pt 12):1744-1750. doi: 10.1107/S2056989016016819. eCollection 2016 Dec 1.

引用本文的文献

1
Crystal structures of (R S)-N-[(1R,2S)-2-benz-yloxy-1-(2,6-di-methyl-phen-yl)prop-yl]-2-methyl-propane-2-sulfinamide and (R S)-N-[(1S,2R)-2-benz-yloxy-1-(2,4,6-tri-methyl-phen-yl)prop-yl]-2-methyl-propane-2-sulfinamide: two related protected 1,2-amino alcohols.（R S）-N-[(1R,2S)-2-苄氧基-1-(2,6-二甲基苯基)丙基]-2-甲基丙烷-2-亚磺酰胺和（R S）-N-[(1S,2R)-2-苄氧基-1-(2,4,6-三甲基苯基)丙基]-2-甲基丙烷-2-亚磺酰胺的晶体结构：两种相关的受保护1,2-氨基醇
Acta Crystallogr Sect E Struct Rep Online. 2014 Oct 24;70(Pt 11):365-9. doi: 10.1107/S1600536814022570. eCollection 2014 Nov 1.
2
tert-Butyl 2-hy-droxy-3-(4-methyl-benzene-sulfonamido)-butano-ate.2-羟基-3-(4-甲基苯磺酰胺基)丁酸叔丁酯
Acta Crystallogr Sect E Struct Rep Online. 2011 Feb 19;67(Pt 3):o648. doi: 10.1107/S1600536811004934.

本文引用的文献

1
cis-N-(2-Hydroxy-cyclo-hexyl)-p-toluene-sulfonamide.顺式-N-(2-羟基环己基)-对甲苯磺酰胺
Acta Crystallogr Sect E Struct Rep Online. 2010 Jan 27;66(Pt 2):o463. doi: 10.1107/S1600536810002151.
2
Stereoselective aziridination of cyclic allylic alcohols using chloramine-T.使用氯胺-T对环状烯丙醇进行立体选择性氮杂环丙烷化反应。
Org Biomol Chem. 2008 Dec 7;6(23):4299-314. doi: 10.1039/b811137e. Epub 2008 Oct 8.
3
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
4
The Os/Cu-Al-hydrotalcite catalysed hydroxylation of alkenes.
Chem Commun (Camb). 2003 Dec 7(23):2922-3. doi: 10.1039/b310686a.