Petrone U, Marascia G, Tucci C, Petrone D, Gaspari G, Angelucci D, Iacobelli S
AZIENDA USL CHIETI,DIV SURG NEPHROL,CHIETI,ITALY. AZIENDA USL CHIETI,DEPT PATHOL,CHIETI,ITALY. UNIV GD ANNUNZIO,DEPT ONCOL,I-66013 CHIETI,ITALY. UNIV GD ANNUNZIO,DEPT NEUROSCI,I-66013 CHIETI,ITALY.
Oncol Rep. 1997 Nov-Dec;4(6):1169-70. doi: 10.3892/or.4.6.1169.
A unique case of carcinosarcoma of the prostate in a 66-year old man is presented. The patient underwent a total prostatectomy under the diagnosis of prostatic carcinoma. Despite adjuvant radiotherapy, the patient died about 3 months after the operation. The surgically resected primary tumor was composed of two histologically distinct elements, an adenocarcinoma and sarcoma with various mesodermal components. These elements were intimately intermingled and transitional forms were often noted. The sarcomatous portion contained areas of chondromatous differentiation. The pathogenesis of this complex neoplasm is discussed.
本文报告了一例66岁男性前列腺癌肉瘤的独特病例。该患者在前列腺癌诊断下接受了前列腺全切术。尽管进行了辅助放疗，但患者在术后约3个月死亡。手术切除的原发肿瘤由两个组织学上不同的成分组成，一个腺癌和一个含有各种中胚层成分的肉瘤。这些成分紧密混合，且经常可见过渡形式。肉瘤部分包含软骨化生区域。本文讨论了这种复杂肿瘤的发病机制。
