Beisse F, Lagrèze W A, Schmucker M
Universitäts-Augenklinik Freiburg, Killianstr., Deutschland.
Ophthalmologe. 2011 May;108(5):425-31. doi: 10.1007/s00347-010-2187-7.
Drug therapy and radiotherapy in Graves' orbitopathy (GO) aim mainly at the inherent soft tissue inflammation. A timely and sustained anti-inflammatory therapy not only alleviates the current symptoms but particularly intends to limit the degree of permanent alterations. It is indicated in active GO of moderate or higher severity. Pharmacologically, glucocorticoids and if appropriate other immunosuppressive agents, such as cyclosporine are given. Adverse effects can complicate the treatment. Retrobulbar irradiation is applied against diplopia due to eye muscle involvement during the active phase.
格雷夫斯眼眶病（GO）的药物治疗和放射治疗主要针对内在的软组织炎症。及时且持续的抗炎治疗不仅能缓解当前症状，尤其旨在限制永久性改变的程度。它适用于中重度活动性GO。在药理学上，给予糖皮质激素，如有必要，还可给予其他免疫抑制剂，如环孢素。不良反应可能使治疗复杂化。在活动期，对因眼肌受累导致的复视进行球后照射。
