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SPECT(单光子发射计算机断层扫描)在 31 名自闭症和类似自闭症的儿童和青少年中的应用。

SPECT (Single Photon Emission Computed Tomography) in 31 children and adolescents with autism and autistic-like conditions.

机构信息

Department of Child and Adolescent Psychiatry, University of Göteborg, Göteborg, Sweden.

出版信息

Eur Child Adolesc Psychiatry. 1993 Jan;2(1):50-9. doi: 10.1007/BF02098830.

DOI:10.1007/BF02098830
PMID:21590529
Abstract

SPECT with Tc-99m-HM-PAO was used in examining 31 patients with autism and autistic-like conditions. Sixteen of these had autistic disorder/autistic-like conditions with associated epilepsy. The autistic disorder group without epilepsy was relatively high functioning. All 31 patients showed reduction of regional cerebral blood flow in the temporal lobes. There was no clear difference between the groups with and without epilepsy, suggesting that seizure disorder per se could not account for the findings.

摘要

我们使用 Tc-99m-HM-PAO SPECT 对 31 名自闭症和类似自闭症的患者进行了检查。其中 16 名患者患有自闭症/类似自闭症,伴有癫痫。不伴癫痫的自闭症患者的功能相对较高。所有 31 名患者的颞叶区域脑血流均减少。伴发癫痫和不伴发癫痫的两组之间没有明显差异,这表明癫痫发作本身并不能解释这些发现。

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本文引用的文献

1
Behavior checklist for identifying severely handicapped individuals with high levels of autistic behavior.用于识别具有高度自闭症行为的重度残疾个体的行为检查表。
J Child Psychol Psychiatry. 1980 Jul;21(3):221-9. doi: 10.1111/j.1469-7610.1980.tb01797.x.
2
Computerized axial tomography in young autistic children.
Am J Psychiatry. 1982 Apr;139(4):510-2. doi: 10.1176/ajp.139.4.510.
3
Computerized tomographic scan findings in patients with autistic behavior.自闭症行为患者的计算机断层扫描结果
自闭症谱系障碍患者额白质和皮质下灰质的高灌注。
Biol Psychiatry. 2019 Apr 1;85(7):584-595. doi: 10.1016/j.biopsych.2018.11.026. Epub 2018 Dec 21.
4
Childhood autism: An appeal for an integrative and psychobiological approach.儿童自闭症:呼吁采用综合心理生物学方法。
Eur Child Adolesc Psychiatry. 1994 Jul;3(3):159-175. doi: 10.1007/BF02720323.
5
Regional Cerebral Glucose Metabolism and its Association with Phenotype and Cognitive Functioning in Patients with Autism.自闭症患者的局部脑葡萄糖代谢及其与表型和认知功能的关联
Indian J Psychol Med. 2017 May-Jun;39(3):262-270. doi: 10.4103/0253-7176.207344.
6
Functional genomics approaches to a primate model of autistic symptomology.针对自闭症症状灵长类动物模型的功能基因组学方法。
J Autism Dev Disord. 2001 Dec;31(6):551-5. doi: 10.1023/a:1013286725596.
Arch Neurol. 1980 Aug;37(8):504-10. doi: 10.1001/archneur.1980.00500570052008.
4
Childhood psychosis and computed tomographic brain scan findings.儿童期精神病与计算机断层扫描脑部扫描结果。
J Autism Dev Disord. 1983 Mar;13(1):19-32. doi: 10.1007/BF01531356.
5
Computed tomography of the brain in children with early infantile autism.早发性婴儿自闭症患儿的脑部计算机断层扫描
Folia Psychiatr Neurol Jpn. 1984;38(1):33-43. doi: 10.1111/j.1440-1819.1984.tb00352.x.
6
Focal cerebral hypoperfusion in children with dysphasia and/or attention deficit disorder.
Arch Neurol. 1984 Aug;41(8):825-9. doi: 10.1001/archneur.1984.04050190031010.
7
Brain metabolism in autism. Resting cerebral glucose utilization rates as measured with positron emission tomography.自闭症中的大脑代谢。通过正电子发射断层扫描测量的静息脑葡萄糖利用率。
Arch Gen Psychiatry. 1985 May;42(5):448-55. doi: 10.1001/archpsyc.1985.01790280026003.
8
Onset at age 14 of a typical autistic syndrome. A case report of a girl with herpes simplex encephalitis.14岁起病的典型自闭症综合征。一例患单纯疱疹性脑炎女孩的病例报告。
J Autism Dev Disord. 1986 Sep;16(3):369-75. doi: 10.1007/BF01531665.
9
Cerebellar structure in autism.
Am J Dis Child. 1987 Dec;141(12):1330-2. doi: 10.1001/archpedi.1987.04460120096044.
10
Hypoplasia of cerebellar vermal lobules VI and VII in autism.自闭症中小脑蚓部小叶VI和VII发育不全。
N Engl J Med. 1988 May 26;318(21):1349-54. doi: 10.1056/NEJM198805263182102.