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Molecular and cellular mechanisms of GABA/benzodiazepine-receptor regulation: electrophysiological and biochemical studies.

作者信息

Farrant M, Gibbs T T, Farb D H

机构信息

Department of Anatomy and Cell Biology, State University of New York, Brooklyn 11203.

出版信息

Neurochem Res. 1990 Feb;15(2):175-91. doi: 10.1007/BF00972208.

DOI:10.1007/BF00972208
PMID:2159123
Abstract
摘要

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Molecular and cellular mechanisms of GABA/benzodiazepine-receptor regulation: electrophysiological and biochemical studies.γ-氨基丁酸/苯二氮䓬受体调节的分子和细胞机制:电生理与生化研究
Neurochem Res. 1990 Feb;15(2):175-91. doi: 10.1007/BF00972208.
2
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The GABA-benzodiazepine interaction fifteen years later.十五年后的γ-氨基丁酸-苯二氮䓬相互作用
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[Izokorin--a new blockader of gamma-aminobutyric acid receptors in the mammalian nervous system].伊佐可林——哺乳动物神经系统中γ-氨基丁酸受体的新型阻滞剂
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Block of an insect central nervous system GABA receptor by cyclodiene and cyclohexane insecticides.环二烯类和环己烷类杀虫剂对昆虫中枢神经系统γ-氨基丁酸受体的阻断作用。
Proc R Soc Lond B Biol Sci. 1989 Jun 22;237(1286):53-61. doi: 10.1098/rspb.1989.0036.
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Dopamine in organophosphate-induced neurotoxicity.多巴胺与有机磷诱导的神经毒性
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Involvement of picrotoxinin receptor in the action of cyclodiene insecticides.苦味毒受体在环二烯类杀虫剂作用中的参与。
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[GABA(A) benzodiazepine receptors and epilepsy].[γ-氨基丁酸A(GABA(A))苯二氮䓬受体与癫痫]
Wien Klin Wochenschr. 1990 Mar 30;102(7):197-201.

引用本文的文献

1
GABAA receptors on rat cerebellar granule cells are potently activated by muscimol but only slightly modulated by the benzodiazepine agonist flunitrazepam.大鼠小脑颗粒细胞上的 GABAA 受体被蝇蕈醇强烈激活,但被苯二氮䓬类激动剂氟硝西泮仅轻度调节。
Amino Acids. 1994 Jun;6(2):155-63. doi: 10.1007/BF00805843.
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Frequency-dependent actions of benzodiazepines on GABAA receptors in cultured murine cerebellar granule cells.苯二氮䓬类药物对培养的小鼠小脑颗粒细胞中GABAA受体的频率依赖性作用。
J Physiol. 1997 Sep 1;503 ( Pt 2)(Pt 2):353-69. doi: 10.1111/j.1469-7793.1997.353bh.x.
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The influence of glycine and related compounds on spinal cord injury-induced spasticity.

本文引用的文献

1
Tolerance during chronic benzodiazepine treatment associated with decreased receptor binding.长期使用苯二氮䓬类药物治疗期间的耐受性与受体结合减少有关。
Eur J Pharmacol. 1981 Apr 9;70(4):453-60. doi: 10.1016/0014-2999(81)90356-3.
2
GABA-mediated synaptic potentials in chick spinal cord and sensory neurons.γ-氨基丁酸介导的鸡脊髓和感觉神经元中的突触电位。
J Neurophysiol. 1981 Apr;45(4):632-43. doi: 10.1152/jn.1981.45.4.632.
3
The inactivation of gamma-aminobutyric acid transaminase in dissociated neuronal cultures from spinal cord.
甘氨酸及相关化合物对脊髓损伤所致痉挛的影响。
Neurochem Res. 1995 Oct;20(10):1203-10. doi: 10.1007/BF00995384.
4
Use of 82Br- radiotracer to study transmembrane halide flux: the effect of a tranquilizing drug, chlordiazepoxide on channel opening of a GABAA receptor.使用⁸²Br放射性示踪剂研究跨膜卤化物通量:镇静药物氯氮卓对GABAA受体通道开放的影响。
J Membr Biol. 1995 Jun;145(3):257-66. doi: 10.1007/BF00232717.
5
Segmental release of amino acid neurotransmitters from transcranial stimulation.经颅刺激引起的氨基酸神经递质的节段性释放。
Neurochem Res. 1991 Jan;16(1):89-94. doi: 10.1007/BF00965834.
脊髓解离神经元培养物中γ-氨基丁酸转氨酶的失活
J Neurochem. 1981 Mar;36(3):985-90. doi: 10.1111/j.1471-4159.1981.tb01690.x.
4
Depression of benzodiazepine binding and diazepam potentiation of GABA-mediated inhibition after chronic exposure of spinal cord cultures to diazepam.脊髓培养物长期暴露于地西泮后苯二氮䓬结合的降低及地西泮对GABA介导的抑制作用的增强
Brain Res. 1983 May 23;268(1):171-6. doi: 10.1016/0006-8993(83)90404-3.
5
GABA conductance of chick spinal cord and dorsal root ganglion neurons in cell culture.细胞培养中鸡脊髓和背根神经节神经元的GABA电导
J Neurophysiol. 1981 Apr;45(4):605-20. doi: 10.1152/jn.1981.45.4.605.
6
Chronic benzodiazepine treatment decreases postsynaptic GABA sensitivity.长期使用苯二氮䓬类药物治疗会降低突触后γ-氨基丁酸(GABA)的敏感性。
Nature. 1984;308(5954):74-7. doi: 10.1038/308074a0.
7
Benzodiazepine receptor binding by membranes from brain cell cultures following chronic treatment with diazepam.用地西泮长期处理后,来自脑细胞培养物的膜与苯二氮䓬受体的结合。
Brain Res. 1983 Dec 12;288(1-2):354-8. doi: 10.1016/0006-8993(83)90117-8.
8
Multiple embryonic benzodiazepine binding sites: evidence for functionality.多个胚胎期苯二氮䓬结合位点:功能证据
Life Sci. 1983 Nov 21;33(21):2061-9. doi: 10.1016/0024-3205(83)90329-6.
9
Characteristics of GABAB receptor binding sites on rat whole brain synaptic membranes.大鼠全脑突触膜上GABAB受体结合位点的特征
Br J Pharmacol. 1983 Jan;78(1):191-206. doi: 10.1111/j.1476-5381.1983.tb09380.x.
10
Drug interactions at the GABA receptor-ionophore complex.γ-氨基丁酸(GABA)受体-离子载体复合物处的药物相互作用。
Annu Rev Pharmacol Toxicol. 1982;22:245-77. doi: 10.1146/annurev.pa.22.040182.001333.