Biofilm Centre, Faculty of Chemistry, University of Duisburg-Essen, Universitätsstrasse 5, D-45141 Essen, Germany.
Colloids Surf B Biointerfaces. 2011 Sep 1;86(2):251-9. doi: 10.1016/j.colsurfb.2011.04.025. Epub 2011 Apr 23.
The biofilm mode of life is only possible because biofilm organisms are transiently immobilized in a matrix of extracellular polymeric substances (EPS), also known as "slime". The matrix can be considered an emerging property of microorganisms, allowing them to form stable synergistic consortia, supporting interaction by signaling molecules and horizontal gene transfer and, eventually being activated by extracellular enzymes which turn the matrix into an external digestion system. As unsightly it is, this matrix is--although seemingly stochastic--a highly differentiated and functional immediate environment for biofilm cells.
生物膜的生活方式之所以成为可能,是因为生物膜中的生物体暂时被固定在细胞外聚合物(EPS)基质中,也被称为“黏液”。基质可以被认为是微生物的一种新兴特性,使它们能够形成稳定的协同共生体,通过信号分子和水平基因转移来支持相互作用,并最终被细胞外酶激活,将基质转化为外部消化系统。尽管这种基质看起来很随机,但它是生物膜细胞的一个高度分化和功能即时环境,尽管不美观。