Twists and turns of DNA methylation.
作者信息
Frauer Carina, Leonhardt Heinrich
机构信息
Center for Integrated Protein Science, Department of Biology II, Ludwig Maximilians University, 82152 Munich, Germany.
出版信息
Proc Natl Acad Sci U S A. 2011 May 31;108(22):8919-20. doi: 10.1073/pnas.1105804108. Epub 2011 May 18.
Abstract
摘要
相似文献
1
Twists and turns of DNA methylation.DNA甲基化的波折起伏
Proc Natl Acad Sci U S A. 2011 May 31;108(22):8919-20. doi: 10.1073/pnas.1105804108. Epub 2011 May 18.
2
Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1).揭示小鼠 DNA 甲基转移酶 1（Dnmt1）维持甲基化的结构基础。
Proc Natl Acad Sci U S A. 2011 May 31;108(22):9055-9. doi: 10.1073/pnas.1019629108. Epub 2011 Apr 25.
3
Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain.结构基础识别 H3K4 甲基化状态的 DNA 甲基转移酶 3A ATRX-DNMT3-DNMT3L 域。
EMBO Rep. 2009 Nov;10(11):1235-41. doi: 10.1038/embor.2009.218. Epub 2009 Oct 16.
4
Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation.DNMT1-DNA 复合物的结构揭示了自身抑制在维持 DNA 甲基化中的作用。
Science. 2011 Feb 25;331(6020):1036-40. doi: 10.1126/science.1195380. Epub 2010 Dec 16.
5
Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B.人类 DNA 甲基转移酶 3B 对 CpG 特异性 DNA 甲基化的结构见解。
Nucleic Acids Res. 2020 Apr 17;48(7):3949-3961. doi: 10.1093/nar/gkaa111.
6
Structure-based mechanistic insights into DNMT1-mediated maintenance DNA methylation.基于结构的 DNMT1 介导的维持 DNA 甲基化的机制见解。
Science. 2012 Feb 10;335(6069):709-12. doi: 10.1126/science.1214453.
7
Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1.CXXC 锌指结构域在 Dnmt1 和 Tet1 中具有不同的结合特性和功能。
PLoS One. 2011 Feb 2;6(2):e16627. doi: 10.1371/journal.pone.0016627.
8
Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition.半甲基化DNA打开UHRF1的封闭构象以促进其对组蛋白的识别。
Nat Commun. 2016 Apr 5;7:11197. doi: 10.1038/ncomms11197.
9
Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1.人UHRF1的SRA结构域识别半甲基化DNA的结构基础。
Nature. 2008 Oct 9;455(7214):822-5. doi: 10.1038/nature07273. Epub 2008 Sep 3.
10
Structure analysis of Entamoeba histolytica DNMT2 (EhMeth).溶组织内阿米巴 DNA 甲基转移酶 2（EhMeth）的结构分析。
PLoS One. 2012;7(6):e38728. doi: 10.1371/journal.pone.0038728. Epub 2012 Jun 21.
引用本文的文献
1
Defects of mutant DNMT1 are linked to a spectrum of neurological disorders.突变型DNMT1的缺陷与一系列神经疾病有关。
Brain. 2015 Apr;138(Pt 4):845-61. doi: 10.1093/brain/awv010. Epub 2015 Feb 11.
2
Genomic survey, gene expression analysis and structural modeling suggest diverse roles of DNA methyltransferases in legumes.基因组调查、基因表达分析和结构建模表明DNA甲基转移酶在豆科植物中具有多种作用。
PLoS One. 2014 Feb 25;9(2):e88947. doi: 10.1371/journal.pone.0088947. eCollection 2014.
3
A novel de novo exon 21 DNMT1 mutation causes cerebellar ataxia, deafness, and narcolepsy in a Brazilian patient.一个新的从头发生的外显子 21 DNMT1 突变导致一名巴西患者出现小脑性共济失调、耳聋和发作性睡病。
Sleep. 2013 Aug 1;36(8):1257-9, 1259A. doi: 10.5665/sleep.2898.
4
Dissection of cell cycle-dependent dynamics of Dnmt1 by FRAP and diffusion-coupled modeling.通过 FRAP 和扩散偶联建模解析 Dnmt1 的细胞周期依赖性动力学。
Nucleic Acids Res. 2013 May;41(9):4860-76. doi: 10.1093/nar/gkt191. Epub 2013 Mar 27.
5
An insight into the various regulatory mechanisms modulating human DNA methyltransferase 1 stability and function.深入了解调节人类 DNA 甲基转移酶 1 稳定性和功能的各种调控机制。
Epigenetics. 2012 Sep;7(9):994-1007. doi: 10.4161/epi.21568. Epub 2012 Aug 16.
6
On the presence and role of human gene-body DNA methylation.关于人类基因体DNA甲基化的存在及作用。
Oncotarget. 2012 Apr;3(4):462-74. doi: 10.18632/oncotarget.497.
本文引用的文献
1
Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1).揭示小鼠 DNA 甲基转移酶 1（Dnmt1）维持甲基化的结构基础。
Proc Natl Acad Sci U S A. 2011 May 31;108(22):9055-9. doi: 10.1073/pnas.1019629108. Epub 2011 Apr 25.
2
The replication focus targeting sequence (RFTS) domain is a DNA-competitive inhibitor of Dnmt1.复制焦点靶向序列（RFTS）结构域是 Dnmt1 的 DNA 竞争性抑制剂。
J Biol Chem. 2011 Apr 29;286(17):15344-51. doi: 10.1074/jbc.M110.209882. Epub 2011 Mar 9.
3
Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1.CXXC 锌指结构域在 Dnmt1 和 Tet1 中具有不同的结合特性和功能。
PLoS One. 2011 Feb 2;6(2):e16627. doi: 10.1371/journal.pone.0016627.
4
Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation.DNMT1-DNA 复合物的结构揭示了自身抑制在维持 DNA 甲基化中的作用。
Science. 2011 Feb 25;331(6020):1036-40. doi: 10.1126/science.1195380. Epub 2010 Dec 16.
5
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA.SRA蛋白Np95通过将Dnmt1招募至甲基化DNA来介导表观遗传继承。
Nature. 2007 Dec 6;450(7171):908-12. doi: 10.1038/nature06397. Epub 2007 Nov 11.
6
The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expression.ICBP90的SRA结构域与DNMT1的一个新结构域之间的相互作用参与了VEGF基因表达的调控。
Oncogene. 2008 Apr 3;27(15):2187-97. doi: 10.1038/sj.onc.1210855. Epub 2007 Oct 15.
7
UHRF1 plays a role in maintaining DNA methylation in mammalian cells.UHRF1在维持哺乳动物细胞中的DNA甲基化方面发挥作用。
Science. 2007 Sep 21;317(5845):1760-4. doi: 10.1126/science.1147939. Epub 2007 Aug 2.
8
Replication-independent chromatin loading of Dnmt1 during G2 and M phases.在G2期和M期，Dnmt1的染色质加载不依赖于复制。
EMBO Rep. 2004 Dec;5(12):1181-6. doi: 10.1038/sj.embor.7400295.
9
The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA.小鼠DNA甲基转移酶Dnmt1的活性受催化结构域与该酶N端部分相互作用的调控，这种相互作用导致该酶在与甲基化DNA结合后发生变构激活。
J Mol Biol. 2001 Jun 22;309(5):1189-99. doi: 10.1006/jmbi.2001.4709.
10
Structure and function of the mouse DNA methyltransferase gene: Dnmt1 shows a tripartite structure.小鼠DNA甲基转移酶基因的结构与功能：Dnmt1呈现出三重结构。
J Mol Biol. 2000 Mar 24;297(2):293-300. doi: 10.1006/jmbi.2000.3588.
Zotero 插件